| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 22 | 22 | 11 | 7 | 3.72 | .316 | 1.37 | 8.1 | 4.2 | 8.5 | 138.0 | 124 | 67 | 57 | 17 | 65 | 130 | 3 | 0 | 0 | 1 | 13 | 2 | 4 | 4.17 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 21 | 21 | 4 | 4 | 6.15 | .321 | 1.40 | 9.5 | 3.2 | 6.3 | 93.2 | 98 | 66 | 64 | 13 | 33 | 65 | 0 | 0 | 0 | 0 | 5 | 2 | 0 | 4.55 |
| SP | Clemens, R.Clemens, Roger # >> | 24 | 1986 | R | 69 | 21 | 21 | 5 | 10 | 5.09 | .315 | 1.36 | 9.6 | 2.7 | 5.2 | 123.2 | 131 | 74 | 70 | 23 | 37 | 71 | 6 | 0 | 0 | 0 | 9 | 3 | 4 | 5.25 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 19 | 19 | 0 | 7 | 7.28 | .370 | 1.69 | 10.7 | 4.5 | 8.5 | 68.0 | 81 | 61 | 55 | 14 | 34 | 64 | 0 | 0 | 0 | 0 | 0 | 5 | 3 | 5.51 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 55 | 0 | 5 | 2 | 2.09 | .268 | 1.10 | 5.5 | 4.4 | 10.6 | 77.1 | 47 | 25 | 18 | 6 | 38 | 91 | 0 | 1 | 2 | 0 | 0 | 0 | 3 | 3.13 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 54 | 0 | 6 | 6 | 4.26 | .291 | 1.22 | 7.7 | 3.4 | 5.3 | 80.1 | 68 | 44 | 38 | 12 | 30 | 47 | 0 | 3 | 4 | 0 | 0 | 1 | 0 | 4.94 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 51 | 0 | 2 | 4 | 4.00 | .341 | 1.56 | 8.3 | 5.7 | 11.3 | 54.0 | 50 | 24 | 24 | 5 | 34 | 68 | 0 | 1 | 2 | 0 | 0 | 0 | 2 | 3.57 |
| RP | Abernathy, T.Abernathy, Ted >> | 34 | 1967 | R | 49 | 47 | 0 | 3 | 4 | 4.03 | .328 | 1.42 | 8.2 | 4.6 | 5.6 | 67.0 | 61 | 36 | 30 | 8 | 34 | 42 | 0 | 1 | 3 | 0 | 0 | 3 | 1 | 4.96 |
| RP | Rodriguez, F.Rodriguez, Felix >> | 29 | 2001 | R | 42 | 39 | 0 | 1 | 3 | 2.65 | .262 | 1.03 | 5.7 | 3.7 | 6.8 | 54.1 | 34 | 17 | 16 | 6 | 22 | 41 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 4.26 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 31 | 0 | 2 | 3 | 3.96 | .320 | 1.39 | 8.3 | 4.3 | 8.1 | 52.1 | 48 | 24 | 23 | 4 | 25 | 47 | 0 | 5 | 0 | 0 | 0 | 1 | 1 | 3.69 |