| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 21 | 21 | 8 | 4 | 4.07 | .325 | 1.42 | 9.8 | 3.0 | 9.5 | 126.0 | 137 | 59 | 57 | 11 | 42 | 133 | 0 | 0 | 0 | 0 | 13 | 3 | 0 | 3.10 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 20 | 20 | 4 | 7 | 5.48 | .341 | 1.50 | 10.5 | 3.1 | 7.4 | 108.1 | 126 | 74 | 66 | 13 | 37 | 89 | 0 | 0 | 0 | 0 | 6 | 5 | 3 | 4.08 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 20 | 20 | 4 | 13 | 5.97 | .371 | 1.75 | 12.1 | 3.6 | 5.3 | 104.0 | 140 | 85 | 69 | 18 | 42 | 61 | 3 | 0 | 0 | 0 | 5 | 2 | 2 | 5.35 |
| RP | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 66 | 0 | 8 | 3 | 2.75 | .258 | 1.02 | 5.1 | 4.1 | 10.3 | 88.1 | 50 | 32 | 27 | 9 | 40 | 101 | 0 | 0 | 2 | 0 | 0 | 2 | 6 | 3.47 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 60 | 0 | 6 | 2 | 4.27 | .317 | 1.38 | 8.6 | 3.9 | 9.3 | 65.1 | 62 | 34 | 31 | 6 | 28 | 67 | 0 | 10 | 3 | 0 | 0 | 1 | 3 | 3.48 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 53 | 0 | 3 | 2 | 3.30 | .286 | 1.19 | 6.8 | 3.9 | 9.0 | 57.1 | 43 | 25 | 21 | 10 | 25 | 57 | 0 | 8 | 2 | 0 | 0 | 1 | 2 | 4.65 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 30 | 0 | 2 | 0 | 2.25 | .270 | 1.11 | 6.0 | 4.0 | 8.5 | 36.0 | 24 | 9 | 9 | 2 | 16 | 34 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3.17 |