| SP | Scherzer, M.Scherzer, Max $ >> | 33 | 2017 | R | 95 | 26 | 26 | 9 | 11 | 3.50 | .303 | 1.30 | 8.0 | 3.7 | 8.2 | 162.0 | 144 | 64 | 63 | 14 | 67 | 148 | 0 | 0 | 0 | 0 | 19 | 0 | 1 | 3.54 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 26 | 26 | 14 | 7 | 3.83 | .276 | 1.14 | 8.3 | 2.0 | 5.6 | 181.0 | 166 | 85 | 77 | 11 | 40 | 113 | 13 | 0 | 0 | 2 | 16 | 1 | 7 | 3.22 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 25 | 25 | 12 | 3 | 4.16 | .305 | 1.29 | 9.1 | 2.6 | 8.3 | 155.2 | 157 | 76 | 72 | 21 | 44 | 143 | 4 | 0 | 0 | 0 | 14 | 4 | 1 | 3.85 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 25 | 25 | 11 | 6 | 3.49 | .299 | 1.26 | 7.6 | 3.7 | 6.2 | 162.1 | 137 | 72 | 63 | 13 | 67 | 112 | 0 | 0 | 0 | 0 | 17 | 4 | 2 | 3.98 |
| SP | Seaver, T.Seaver, Tom # >> | 27 | 1971 | R | 70 | 25 | 25 | 8 | 10 | 4.74 | .307 | 1.30 | 8.9 | 2.8 | 8.0 | 165.1 | 163 | 88 | 87 | 20 | 52 | 147 | 8 | 0 | 0 | 1 | 11 | 5 | 2 | 3.83 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 65 | 0 | 5 | 3 | 2.45 | .290 | 1.21 | 7.2 | 3.6 | 10.3 | 92.0 | 74 | 28 | 25 | 2 | 37 | 105 | 0 | 5 | 2 | 0 | 0 | 2 | 7 | 2.27 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 54 | 0 | 7 | 6 | 4.46 | .304 | 1.27 | 7.7 | 3.8 | 10.1 | 68.2 | 58 | 34 | 34 | 14 | 29 | 76 | 0 | 5 | 3 | 0 | 0 | 3 | 0 | 4.85 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 33 | 0 | 1 | 2 | 4.47 | .300 | 1.26 | 9.4 | 2.0 | 8.6 | 44.1 | 46 | 24 | 22 | 7 | 10 | 42 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.91 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 23 | 0 | 2 | 4 | 6.49 | .336 | 1.52 | 11.4 | 2.4 | 8.3 | 26.1 | 33 | 19 | 19 | 10 | 7 | 24 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 6.96 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 14 | 0 | 1 | 0 | 4.86 | .306 | 1.26 | 8.4 | 3.4 | 7.3 | 16.2 | 15 | 10 | 9 | 2 | 6 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.31 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 15 | 0 | 1 | 1 | 5.03 | .337 | 1.53 | 10.4 | 3.8 | 8.5 | 19.2 | 22 | 11 | 11 | 5 | 8 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.79 |