| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 9 | 9 | 2 | 3 | 7.68 | .379 | 1.71 | 11.0 | 4.4 | 8.3 | 41.0 | 50 | 36 | 35 | 10 | 20 | 38 | 0 | 0 | 0 | 0 | 3 | 5 | 1 | 6.15 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 9 | 9 | 3 | 5 | 4.11 | .298 | 1.22 | 8.0 | 3.1 | 3.5 | 61.1 | 54 | 30 | 28 | 7 | 21 | 24 | 4 | 0 | 0 | 0 | 5 | 3 | 1 | 4.89 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 8 | 8 | 5 | 1 | 2.85 | .268 | 1.08 | 7.3 | 2.5 | 6.8 | 53.2 | 43 | 17 | 17 | 8 | 15 | 40 | 0 | 0 | 0 | 0 | 5 | 1 | 1 | 4.36 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 8 | 8 | 2 | 1 | 4.22 | .304 | 1.28 | 7.8 | 3.7 | 4.4 | 53.1 | 46 | 25 | 25 | 7 | 22 | 26 | 1 | 0 | 0 | 0 | 3 | 2 | 0 | 5.09 |
| RP | Kimbrel, C.Kimbrel, Craig $ >> | 24 | 2012 | R | 100 | 22 | 0 | 4 | 0 | 2.65 | .266 | 1.09 | 5.6 | 4.2 | 10.1 | 34.0 | 21 | 10 | 10 | 3 | 16 | 38 | 0 | 2 | 0 | 0 | 0 | 0 | 3 | 3.32 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 24 | 0 | 4 | 1 | 2.61 | .250 | 0.97 | 6.1 | 2.6 | 8.4 | 31.0 | 21 | 10 | 9 | 2 | 9 | 29 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 2.94 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 80 | 16 | 0 | 0 | 2 | 4.26 | .269 | 1.11 | 9.0 | 0.9 | 10.4 | 19.0 | 19 | 9 | 9 | 2 | 2 | 22 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 2.37 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 11 | 0 | 0 | 0 | 1.50 | .250 | 1.00 | 3.8 | 5.3 | 10.5 | 12.0 | 5 | 2 | 2 | 1 | 7 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.50 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 74 | 8 | 0 | 1 | 0 | 1.00 | .270 | 1.11 | 8.0 | 2.0 | 13.0 | 9.0 | 8 | 1 | 1 | 0 | 2 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.78 |