| SP | Koufax, S.Koufax, Sandy # >> | 30 | 1965 | L | 98 | 26 | 26 | 10 | 13 | 3.95 | .288 | 1.19 | 8.4 | 2.3 | 7.4 | 203.0 | 189 | 91 | 89 | 23 | 53 | 166 | 10 | 0 | 0 | 3 | 14 | 4 | 7 | 3.68 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 25 | 25 | 9 | 12 | 5.49 | .338 | 1.52 | 10.0 | 3.7 | 4.2 | 159.0 | 176 | 101 | 97 | 20 | 66 | 74 | 2 | 0 | 0 | 0 | 9 | 2 | 1 | 4.99 |
| SP | Chesbro, J.Chesbro, Jack # >> | 30 | 1904 | R | 65 | 25 | 25 | 7 | 14 | 5.40 | .331 | 1.47 | 9.7 | 3.6 | 5.0 | 163.1 | 175 | 101 | 98 | 24 | 65 | 91 | 7 | 0 | 0 | 1 | 11 | 2 | 3 | 5.03 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 65 | 0 | 4 | 2 | 3.05 | .271 | 1.10 | 6.3 | 3.7 | 7.2 | 103.1 | 72 | 35 | 35 | 8 | 42 | 82 | 0 | 5 | 4 | 0 | 0 | 1 | 0 | 3.67 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 33 | 0 | 4 | 1 | 3.26 | .318 | 1.40 | 9.0 | 3.8 | 8.8 | 38.2 | 38 | 14 | 14 | 3 | 16 | 37 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 3.34 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 58 | 24 | 0 | 0 | 1 | 3.81 | .304 | 1.31 | 8.0 | 3.8 | 7.3 | 26.0 | 23 | 11 | 11 | 4 | 11 | 21 | 0 | 2 | 0 | 0 | 0 | 0 | 3 | 4.65 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 50 | 21 | 0 | 0 | 1 | 4.10 | .288 | 1.22 | 7.3 | 3.8 | 6.2 | 26.1 | 21 | 12 | 12 | 1 | 11 | 18 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.38 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 59 | 1 | 0 | 0 | 0 | 13.50 | .600 | 4.50 | - | - | - | 0.2 | 3 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 11 | 0 | 0 | 1 | 6.43 | .354 | 1.64 | 11.6 | 3.2 | 3.2 | 14.0 | 18 | 10 | 10 | 1 | 5 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.29 |