| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 34 | 34 | 18 | 15 | 3.72 | .284 | 1.18 | 8.8 | 1.9 | 8.2 | 256.2 | 249 | 118 | 106 | 32 | 54 | 233 | 10 | 0 | 0 | 2 | 21 | 3 | 4 | 3.47 |
| SP | Horlen, J.Horlen, Joe # >> | 27 | 1964 | R | 78 | 32 | 32 | 15 | 14 | 4.50 | .305 | 1.29 | 8.3 | 3.3 | 5.8 | 218.0 | 200 | 122 | 109 | 25 | 81 | 140 | 4 | 0 | 0 | 1 | 17 | 6 | 6 | 4.40 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 32 | 32 | 3 | 21 | 6.36 | .350 | 1.61 | 10.6 | 3.9 | 4.5 | 203.2 | 238 | 148 | 144 | 31 | 89 | 102 | 2 | 0 | 0 | 0 | 8 | 2 | 4 | 5.33 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 98 | 78 | 0 | 3 | 6 | 3.30 | .284 | 1.17 | 8.0 | 2.6 | 9.5 | 109.0 | 97 | 47 | 40 | 9 | 31 | 115 | 0 | 4 | 3 | 0 | 0 | 2 | 6 | 2.87 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 86 | 0 | 1 | 7 | 4.02 | .298 | 1.26 | 8.4 | 2.9 | 7.8 | 107.1 | 100 | 53 | 48 | 10 | 35 | 93 | 0 | 11 | 3 | 0 | 0 | 2 | 2 | 3.51 |
| RP | Zimmerman, J.Zimmerman, Jeff # >> | 27 | 1999 | R | 70 | 64 | 0 | 3 | 3 | 5.28 | .368 | 1.72 | 10.6 | 4.9 | 5.3 | 75.0 | 88 | 49 | 44 | 11 | 41 | 44 | 0 | 6 | 2 | 0 | 0 | 2 | 1 | 5.45 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 52 | 0 | 2 | 1 | 3.20 | .300 | 1.27 | 5.8 | 5.6 | 10.8 | 59.0 | 38 | 21 | 21 | 9 | 37 | 71 | 0 | 3 | 1 | 0 | 0 | 1 | 3 | 4.51 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 1 | 0 | 0 | 0 | 16.20 | .444 | 2.40 | 21.0 | 3.0 | 9.0 | 3.1 | 7 | 6 | 6 | 2 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.67 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 57 | 24 | 0 | 2 | 1 | 4.61 | .369 | 1.73 | 9.9 | 5.7 | 4.8 | 41.0 | 45 | 25 | 21 | 5 | 26 | 22 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 5.49 |