| SP | Johnson, W.Johnson, Walter >> | 26 | 1913 | R | 95 | 21 | 21 | 7 | 7 | 3.98 | .295 | 1.25 | 9.3 | 2.0 | 4.4 | 138.0 | 142 | 71 | 61 | 13 | 31 | 68 | 1 | 0 | 0 | 0 | 10 | 0 | 1 | 3.91 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 20 | 20 | 6 | 12 | 5.17 | .343 | 1.55 | 9.1 | 4.9 | 8.2 | 118.1 | 119 | 79 | 68 | 17 | 64 | 107 | 0 | 0 | 0 | 0 | 6 | 2 | 5 | 4.74 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 20 | 20 | 8 | 5 | 3.80 | .311 | 1.33 | 8.6 | 3.4 | 4.8 | 149.1 | 142 | 84 | 63 | 11 | 56 | 80 | 4 | 0 | 0 | 0 | 12 | 4 | 5 | 4.09 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 18 | 18 | 9 | 6 | 3.86 | .299 | 1.27 | 8.3 | 3.1 | 6.2 | 126.0 | 116 | 65 | 54 | 13 | 44 | 87 | 2 | 0 | 0 | 1 | 9 | 1 | 5 | 4.03 |
| SU | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 36 | 0 | 2 | 3 | 2.83 | .307 | 1.33 | 8.1 | 4.0 | 8.6 | 41.1 | 37 | 17 | 13 | 3 | 18 | 39 | 0 | 3 | 4 | 0 | 0 | 0 | 0 | 3.37 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 39 | 0 | 1 | 2 | 5.40 | .302 | 1.30 | 8.6 | 3.2 | 10.8 | 40.0 | 38 | 24 | 24 | 11 | 14 | 48 | 0 | 1 | 3 | 0 | 0 | 0 | 1 | 5.23 |
| CL | Hoffman, T.Hoffman, Trevor † >> | 31 | 1998 | R | 75 | 37 | 0 | 5 | 4 | 1.05 | .228 | 0.88 | 4.6 | 3.3 | 8.6 | 43.0 | 22 | 9 | 5 | 1 | 16 | 41 | 0 | 19 | 2 | 0 | 0 | 0 | 3 | 2.51 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 29 | 0 | 2 | 1 | 5.18 | .317 | 1.30 | 9.0 | 2.7 | 9.8 | 33.0 | 33 | 20 | 19 | 5 | 10 | 36 | 0 | 0 | 0 | 0 | 0 | 3 | 5 | 3.97 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 1 | 1 | 0 | 1 | 4.05 | .310 | 1.35 | 9.0 | 4.5 | 3.0 | 6.2 | 6 | 3 | 3 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 3.83 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 6 | 0 | 0 | 0 | 1.80 | .250 | 1.00 | 7.2 | 1.8 | 3.6 | 5.0 | 4 | 1 | 1 | 1 | 1 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.40 |