| SP | Arrieta, J.Arrieta, Jake $ >> | 29 | 2015 | R | 93 | 36 | 36 | 16 | 11 | 3.16 | .271 | 1.10 | 7.0 | 3.0 | 7.2 | 219.1 | 170 | 82 | 77 | 20 | 72 | 175 | 1 | 0 | 0 | 0 | 19 | 2 | 7 | 3.60 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 35 | 35 | 18 | 8 | 3.03 | .284 | 1.18 | 7.8 | 2.8 | 5.3 | 235.0 | 204 | 87 | 79 | 14 | 74 | 139 | 2 | 0 | 0 | 0 | 25 | 1 | 4 | 3.55 |
| SP | Alexander, P.Alexander, Pete † $ >> | 28 | 1915 | R | 88 | 34 | 34 | 19 | 8 | 2.47 | .265 | 1.08 | 7.1 | 2.6 | 4.9 | 233.1 | 183 | 77 | 64 | 14 | 68 | 126 | 6 | 0 | 0 | 3 | 25 | 2 | 3 | 3.60 |
| SP | Ryan, N.Ryan, Nolan # $$ >> | 44 | 1991 | R | 73 | 33 | 33 | 12 | 10 | 3.52 | .287 | 1.19 | 6.9 | 3.8 | 7.7 | 207.1 | 159 | 83 | 81 | 19 | 88 | 177 | 2 | 0 | 0 | 1 | 21 | 3 | 9 | 3.80 |
| CL | Adams, M.Adams, Mike † >> | 31 | 2009 | R | 99 | 89 | 0 | 7 | 3 | 2.43 | .260 | 1.04 | 5.8 | 3.6 | 9.4 | 114.2 | 73 | 36 | 31 | 10 | 46 | 119 | 0 | 13 | 4 | 0 | 0 | 2 | 1 | 3.32 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 56 | 0 | 5 | 7 | 3.00 | .256 | 1.02 | 6.4 | 2.7 | 6.3 | 63.0 | 45 | 22 | 21 | 7 | 19 | 44 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 4.00 |
| RP | Capps, C.Capps, Carter # >> | 24 | 2015 | R | 85 | 39 | 0 | 4 | 0 | 4.19 | .293 | 1.22 | 8.5 | 2.6 | 9.9 | 38.2 | 36 | 19 | 18 | 6 | 11 | 42 | 0 | 3 | 2 | 0 | 0 | 1 | 3 | 3.79 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 18 | 0 | 1 | 2 | 5.03 | .337 | 1.53 | 8.5 | 5.7 | 6.2 | 19.2 | 18 | 12 | 11 | 2 | 12 | 13 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 4.89 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 62 | 10 | 0 | 1 | 0 | 3.09 | .300 | 1.29 | 6.5 | 5.7 | 4.9 | 11.2 | 8 | 4 | 4 | 1 | 7 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.00 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 48 | 39 | 0 | 3 | 5 | 4.59 | .321 | 1.38 | 8.3 | 4.2 | 7.5 | 80.1 | 74 | 41 | 41 | 7 | 37 | 67 | 0 | 0 | 0 | 0 | 0 | 3 | 4 | 3.96 |