| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 27 | 27 | 15 | 5 | 2.88 | .276 | 1.11 | 7.3 | 2.7 | 7.6 | 175.0 | 142 | 61 | 56 | 11 | 53 | 147 | 0 | 0 | 0 | 0 | 21 | 5 | 5 | 3.13 |
| SP | Leonard, D.Leonard, Dutch $ >> | 22 | 1914 | L | 91 | 26 | 26 | 14 | 7 | 3.69 | .258 | 1.03 | 6.2 | 3.1 | 5.3 | 165.2 | 114 | 72 | 68 | 19 | 57 | 98 | 4 | 0 | 0 | 2 | 16 | 2 | 1 | 4.38 |
| SP | Brown, M.Brown, Mordecai # >> | 32 | 1908 | R | 85 | 25 | 25 | 9 | 8 | 4.23 | .276 | 1.12 | 8.2 | 1.9 | 3.6 | 151.0 | 137 | 74 | 71 | 10 | 32 | 60 | 1 | 0 | 0 | 1 | 14 | 4 | 3 | 3.78 |
| SP | McDowell, S.McDowell, Sam † >> | 26 | 1968 | L | 45 | 24 | 23 | 13 | 8 | 3.45 | .311 | 1.31 | 7.5 | 4.3 | 6.5 | 174.2 | 145 | 73 | 67 | 18 | 83 | 126 | 7 | 0 | 0 | 0 | 11 | 8 | 2 | 4.47 |
| RP | Eckersley, D.Eckersley, Dennis $ >> | 36 | 1990 | R | 88 | 62 | 0 | 3 | 6 | 3.18 | .276 | 1.13 | 7.9 | 2.2 | 6.4 | 85.0 | 75 | 30 | 30 | 9 | 21 | 60 | 0 | 9 | 4 | 0 | 0 | 1 | 0 | 3.74 |
| RP | Percival, T.Percival, Troy # >> | 26 | 1995 | R | 82 | 43 | 0 | 4 | 2 | 5.08 | .353 | 1.63 | 7.1 | 7.9 | 7.6 | 33.2 | 26 | 20 | 19 | 6 | 29 | 28 | 0 | 2 | 4 | 0 | 0 | 0 | 1 | 6.30 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 33 | 0 | 3 | 4 | 3.47 | .319 | 1.40 | 8.0 | 4.8 | 10.0 | 36.1 | 32 | 14 | 14 | 5 | 19 | 40 | 0 | 2 | 0 | 0 | 0 | 0 | 3 | 4.17 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 62 | 4 | 0 | 0 | 0 | 0.00 | .273 | 1.13 | 9.0 | 1.8 | 9.0 | 5.1 | 5 | 0 | 0 | 0 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1.60 |