| SP | deGrom, J.deGrom, Jacob # $ >> | 33 | 2021 | R | 100 | 34 | 34 | 15 | 11 | 3.16 | .260 | 1.03 | 6.5 | 2.8 | 9.4 | 213.2 | 155 | 82 | 75 | 28 | 66 | 222 | 2 | 0 | 0 | 0 | 22 | 4 | 0 | 3.61 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 32 | 32 | 7 | 18 | 4.61 | .302 | 1.29 | 9.5 | 2.1 | 9.1 | 193.1 | 204 | 109 | 99 | 28 | 46 | 195 | 6 | 0 | 0 | 1 | 18 | 1 | 1 | 3.60 |
| SP | Score, H.Score, Herb # >> | 23 | 1956 | L | 41 | 22 | 22 | 10 | 5 | 4.18 | .306 | 1.30 | 7.6 | 4.2 | 8.4 | 131.1 | 110 | 65 | 61 | 19 | 61 | 122 | 5 | 0 | 0 | 2 | 11 | 3 | 3 | 4.49 |
| RP | Kimbrel, C.Kimbrel, Craig $$ >> | 24 | 2012 | R | 100 | 75 | 0 | 8 | 4 | 2.27 | .255 | 1.00 | 5.2 | 3.8 | 10.4 | 107.0 | 62 | 30 | 27 | 6 | 45 | 124 | 0 | 5 | 6 | 0 | 0 | 3 | 3 | 2.76 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 66 | 0 | 2 | 5 | 2.61 | .287 | 1.20 | 7.0 | 3.8 | 10.0 | 82.2 | 64 | 28 | 24 | 9 | 35 | 91 | 0 | 8 | 2 | 0 | 0 | 1 | 0 | 3.52 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 22 | 0 | 1 | 2 | 2.83 | .277 | 1.01 | 5.1 | 4.2 | 7.1 | 28.2 | 16 | 12 | 9 | 1 | 13 | 22 | 0 | 2 | 1 | 0 | 0 | 4 | 0 | 3.71 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 36 | 0 | 4 | 2 | 3.52 | .320 | 1.36 | 7.3 | 5.0 | 11.4 | 38.1 | 31 | 15 | 15 | 7 | 21 | 48 | 0 | 3 | 0 | 0 | 0 | 2 | 2 | 4.68 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 68 | 49 | 0 | 4 | 7 | 4.13 | .301 | 1.26 | 7.4 | 4.1 | 4.7 | 80.2 | 66 | 40 | 37 | 12 | 36 | 42 | 0 | 7 | 2 | 0 | 0 | 2 | 3 | 5.33 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 23 | 0 | 2 | 0 | 6.35 | .351 | 1.62 | 10.3 | 4.5 | 9.0 | 28.1 | 32 | 20 | 20 | 2 | 14 | 28 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 3.43 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 20 | 2 | 4 | 3 | 5.56 | .340 | 1.53 | 8.5 | 5.4 | 3.9 | 90.2 | 85 | 72 | 56 | 16 | 54 | 39 | 0 | 2 | 0 | 0 | 0 | 1 | 1 | 6.28 |