| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 92 | 16 | 16 | 6 | 6 | 3.84 | .309 | 1.30 | 8.4 | 3.4 | 7.9 | 100.2 | 93 | 46 | 43 | 9 | 38 | 88 | 3 | 0 | 0 | 2 | 8 | 4 | 0 | 3.67 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 13 | 9 | 4 | 4 | 3.99 | .339 | 1.53 | 8.4 | 5.4 | 4.6 | 76.2 | 71 | 40 | 34 | 8 | 46 | 39 | 0 | 0 | 0 | 0 | 5 | 1 | 1 | 5.20 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 15 | 15 | 4 | 9 | 5.02 | .317 | 1.35 | 9.9 | 2.2 | 4.1 | 86.0 | 95 | 48 | 48 | 13 | 21 | 39 | 1 | 0 | 0 | 1 | 6 | 4 | 2 | 4.93 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 48 | 0 | 0 | 1 | 3.29 | .300 | 1.27 | 6.8 | 4.7 | 9.5 | 52.0 | 39 | 21 | 19 | 6 | 27 | 55 | 0 | 8 | 2 | 0 | 0 | 1 | 0 | 4.00 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 55 | 0 | 3 | 1 | 3.24 | .313 | 1.34 | 8.3 | 4.0 | 10.1 | 41.2 | 38 | 15 | 15 | 4 | 18 | 46 | 0 | 2 | 1 | 0 | 0 | 1 | 3 | 3.41 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 25 | 0 | 2 | 3 | 9.00 | .396 | 1.93 | 11.7 | 5.7 | 10.7 | 27.0 | 35 | 27 | 27 | 6 | 17 | 32 | 0 | 3 | 2 | 0 | 0 | 1 | 4 | 5.52 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 32 | 0 | 4 | 1 | 3.78 | .355 | 1.65 | 7.1 | 7.9 | 9.3 | 33.1 | 26 | 14 | 14 | 3 | 29 | 34 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 4.76 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 40 | 0 | 1 | 2 | 5.05 | .344 | 1.57 | 8.5 | 5.9 | 10.3 | 35.2 | 33 | 21 | 20 | 4 | 23 | 40 | 0 | 3 | 2 | 0 | 0 | 0 | 1 | 4.17 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 16 | 7 | 2 | 4 | 7.98 | .351 | 1.60 | 10.7 | 3.7 | 7.6 | 53.0 | 63 | 48 | 47 | 14 | 22 | 45 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 6.04 |