| SP | Jenkins, F.Jenkins, Fergie >> | 32 | 1974 | R | 38 | 31 | 31 | 6 | 14 | 4.83 | .315 | 1.35 | 9.7 | 2.4 | 6.7 | 188.1 | 203 | 134 | 101 | 31 | 51 | 139 | 6 | 0 | 0 | 0 | 13 | 6 | 3 | 4.57 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 95 | 32 | 32 | 12 | 15 | 4.78 | .303 | 1.29 | 8.2 | 3.5 | 10.0 | 186.1 | 169 | 119 | 99 | 33 | 72 | 206 | 0 | 0 | 0 | 0 | 14 | 2 | 3 | 4.28 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 62 | 29 | 29 | 5 | 16 | 6.01 | .335 | 1.48 | 10.4 | 3.0 | 7.1 | 157.1 | 181 | 122 | 105 | 30 | 52 | 124 | 1 | 0 | 0 | 1 | 10 | 5 | 0 | 4.99 |
| CL | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 94 | 77 | 0 | 2 | 6 | 3.42 | .307 | 1.30 | 7.1 | 4.7 | 11.7 | 79.0 | 62 | 33 | 30 | 9 | 41 | 103 | 0 | 21 | 3 | 0 | 0 | 2 | 0 | 3.51 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 85 | 83 | 0 | 5 | 5 | 3.82 | .301 | 1.26 | 9.2 | 2.2 | 9.9 | 101.1 | 103 | 51 | 43 | 14 | 25 | 111 | 0 | 2 | 1 | 0 | 0 | 3 | 0 | 3.44 |
| SU | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 73 | 79 | 0 | 0 | 2 | 4.31 | .337 | 1.49 | 8.5 | 4.9 | 10.7 | 79.1 | 75 | 49 | 38 | 9 | 43 | 94 | 0 | 5 | 5 | 0 | 0 | 3 | 3 | 3.85 |
| RP | Marshall, M.Marshall, Mike >> | 31 | 1974 | R | 1 | 70 | 0 | 1 | 4 | 7.14 | .396 | 1.94 | 13.8 | 3.7 | 7.4 | 104.2 | 160 | 103 | 83 | 19 | 43 | 86 | 0 | 1 | 2 | 0 | 0 | 3 | 5 | 5.05 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 70 | 1 | 1 | 0 | 1 | 27.00 | .545 | 3.60 | 36.0 | 18.0 | 18.0 | 1.2 | 4 | 6 | 5 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.00 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 25 | 10 | 0 | 0 | 2 | 3.45 | .329 | 1.40 | 10.2 | 3.0 | 7.8 | 15.2 | 17 | 11 | 6 | 2 | 5 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.20 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 65 | 39 | 1 | 3 | 9 | 6.14 | .339 | 1.51 | 10.8 | 2.8 | 11.1 | 73.1 | 88 | 61 | 50 | 19 | 23 | 90 | 0 | 2 | 3 | 0 | 0 | 2 | 1 | 4.95 |