| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 75 | 6 | 6 | 2 | 2 | 3.95 | .317 | 1.35 | 10.7 | 1.7 | 9.7 | 27.1 | 32 | 14 | 12 | 5 | 5 | 29 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.93 |
| SP | Hudson, D.Hudson, Daniel # >> | 23 | 2010 | R | 72 | 6 | 6 | 3 | 2 | 4.12 | .333 | 1.47 | 10.2 | 3.2 | 5.5 | 39.1 | 44 | 18 | 18 | 2 | 14 | 24 | 1 | 0 | 0 | 0 | 4 | 1 | 0 | 3.59 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 88 | 7 | 5 | 1 | 3 | 6.15 | .368 | 1.75 | 10.7 | 5.2 | 7.3 | 26.1 | 31 | 19 | 18 | 5 | 15 | 21 | 0 | 0 | 1 | 0 | 2 | 0 | 0 | 5.62 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 96 | 15 | 0 | 0 | 1 | 3.86 | .288 | 1.21 | 5.8 | 5.1 | 9.6 | 14.0 | 9 | 6 | 6 | 1 | 8 | 15 | 0 | 8 | 1 | 0 | 0 | 0 | 0 | 3.50 |
| SU | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 88 | 18 | 0 | 0 | 0 | 3.15 | .310 | 1.30 | 9.0 | 2.7 | 7.2 | 20.0 | 20 | 7 | 7 | 4 | 6 | 16 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.05 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 82 | 13 | 0 | 2 | 1 | 4.19 | .284 | 1.19 | 7.6 | 3.3 | 11.8 | 19.1 | 16 | 9 | 9 | 5 | 7 | 25 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.89 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 77 | 14 | 0 | 0 | 1 | 4.12 | .253 | 0.97 | 7.1 | 1.9 | 8.1 | 19.2 | 15 | 9 | 9 | 3 | 4 | 17 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.05 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 66 | 11 | 0 | 0 | 1 | 5.60 | .303 | 1.25 | 8.5 | 3.2 | 9.5 | 17.2 | 16 | 11 | 11 | 3 | 6 | 18 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.41 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 66 | 1 | 0 | 0 | 0 | 0.00 | .500 | 3.00 | - | - | - | 0.1 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |