| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 34 | 34 | 22 | 8 | 2.33 | .243 | 0.95 | 6.5 | 2.0 | 9.7 | 262.1 | 190 | 69 | 68 | 24 | 58 | 283 | 6 | 0 | 0 | 3 | 28 | 4 | 4 | 2.74 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 90 | 33 | 33 | 13 | 15 | 3.38 | .290 | 1.20 | 8.6 | 2.2 | 6.5 | 242.1 | 231 | 94 | 91 | 33 | 59 | 174 | 7 | 0 | 0 | 1 | 24 | 7 | 5 | 4.15 |
| SP | Hernandez, F.Hernandez, Felix # >> | 28 | 2014 | R | 87 | 32 | 32 | 20 | 5 | 3.70 | .276 | 1.13 | 7.9 | 2.3 | 8.4 | 240.2 | 211 | 107 | 99 | 35 | 60 | 224 | 9 | 0 | 0 | 0 | 18 | 4 | 11 | 3.83 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 74 | 31 | 31 | 15 | 10 | 4.70 | .302 | 1.28 | 8.6 | 2.9 | 6.2 | 206.2 | 197 | 110 | 108 | 37 | 67 | 142 | 13 | 0 | 0 | 2 | 14 | 4 | 5 | 4.99 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 82 | 0 | 9 | 6 | 2.35 | .230 | 0.87 | 5.0 | 2.8 | 9.9 | 115.0 | 64 | 31 | 30 | 7 | 36 | 126 | 0 | 14 | 1 | 0 | 0 | 3 | 4 | 2.62 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 59 | 0 | 3 | 2 | 1.43 | .216 | 0.81 | 4.7 | 2.6 | 8.7 | 63.0 | 33 | 10 | 10 | 3 | 18 | 61 | 0 | 11 | 1 | 0 | 0 | 1 | 4 | 2.59 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 30 | 0 | 2 | 1 | 3.56 | .289 | 1.22 | 9.3 | 1.8 | 9.9 | 30.1 | 31 | 12 | 12 | 4 | 6 | 33 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 3.13 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 76 | 16 | 0 | 1 | 1 | 2.18 | .205 | 0.77 | 5.4 | 1.8 | 9.9 | 20.2 | 12 | 5 | 5 | 1 | 4 | 22 | 0 | 3 | 0 | 0 | 0 | 0 | 3 | 2.05 |
| RP | Quisenberry, D.Quisenberry, Dan >> | 30 | 1983 | R | 25 | 19 | 0 | 0 | 1 | 3.12 | .278 | 1.15 | 8.3 | 2.1 | 5.9 | 26.0 | 24 | 9 | 9 | 3 | 6 | 17 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.88 |