| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 5 | 5 | 0 | 3 | 4.85 | .299 | 1.25 | 8.4 | 3.1 | 10.6 | 29.2 | 27 | 17 | 16 | 7 | 10 | 34 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 4.93 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 5 | 5 | 0 | 3 | 7.94 | .398 | 1.85 | 11.9 | 5.3 | 5.3 | 22.2 | 29 | 22 | 20 | 6 | 13 | 13 | 0 | 0 | 0 | 0 | 1 | 3 | 3 | 7.55 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 4 | 4 | 0 | 1 | 12.05 | .467 | 2.57 | 17.5 | 6.5 | 5.5 | 18.2 | 35 | 28 | 25 | 8 | 13 | 11 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 9.89 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 4 | 4 | 0 | 3 | 7.77 | .411 | 2.09 | 14.7 | 4.1 | 4.9 | 22.0 | 36 | 20 | 19 | 3 | 10 | 12 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 5.05 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 12 | 0 | 0 | 1 | 3.78 | .306 | 1.26 | 7.3 | 4.5 | 7.9 | 16.2 | 13 | 10 | 7 | 1 | 8 | 14 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.75 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 13 | 0 | 2 | 1 | 5.85 | .268 | 1.00 | 8.6 | 0.5 | 8.6 | 20.0 | 19 | 13 | 13 | 4 | 1 | 19 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.15 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 12 | 0 | 0 | 0 | 5.09 | .329 | 1.47 | 10.6 | 3.2 | 5.8 | 17.2 | 20 | 10 | 10 | 4 | 6 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5.82 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 61 | 12 | 0 | 0 | 1 | 5.52 | .313 | 1.36 | 9.6 | 3.2 | 7.7 | 14.2 | 15 | 9 | 9 | 0 | 5 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.36 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |