| SP | Cortes Jr., N.Cortes Jr., Nestor >> | 27 | 2022 | L | 97 | 34 | 34 | 13 | 11 | 4.02 | .284 | 1.17 | 7.8 | 2.7 | 10.0 | 208.0 | 180 | 93 | 93 | 35 | 63 | 230 | 0 | 0 | 0 | 0 | 17 | 4 | 4 | 3.94 |
| SP | Severino, L.Severino, Luis >> | 28 | 2022 | R | 90 | 33 | 33 | 16 | 5 | 4.22 | .298 | 1.24 | 7.5 | 3.7 | 8.9 | 179.1 | 149 | 86 | 84 | 29 | 74 | 177 | 0 | 0 | 0 | 0 | 16 | 5 | 0 | 4.45 |
| SP | Sabathia, C.Sabathia, CC † # >> | 29 | 2009 | L | 54 | 32 | 31 | 18 | 6 | 4.11 | .297 | 1.25 | 8.6 | 2.7 | 6.9 | 223.1 | 213 | 107 | 102 | 31 | 67 | 170 | 3 | 0 | 0 | 1 | 17 | 3 | 6 | 4.22 |
| CL | Marinaccio, R.Marinaccio, Ron † >> | 26 | 2022 | R | 87 | 56 | 0 | 8 | 4 | 2.34 | .332 | 1.46 | 7.1 | 6.2 | 9.6 | 57.2 | 45 | 15 | 15 | 1 | 39 | 61 | 0 | 25 | 1 | 0 | 0 | 2 | 5 | 3.25 |
| RP | Holmes, C.Holmes, Clay >> | 29 | 2022 | R | 73 | 87 | 0 | 3 | 2 | 3.11 | .273 | 1.05 | 7.1 | 2.5 | 9.0 | 66.2 | 52 | 23 | 23 | 7 | 18 | 66 | 0 | 2 | 3 | 0 | 0 | 5 | 3 | 3.42 |
| RP | Rivera, M.Rivera, Mariano >> | 40 | 2009 | R | 85 | 60 | 0 | 9 | 4 | 2.91 | .262 | 1.06 | 7.3 | 2.4 | 8.3 | 52.2 | 42 | 17 | 17 | 7 | 14 | 48 | 0 | 4 | 4 | 0 | 0 | 0 | 0 | 3.71 |
| RP | Wickman, B.Wickman, Bob >> | 25 | 1994 | R | 44 | 57 | 0 | 2 | 1 | 3.01 | .297 | 1.24 | 8.2 | 3.0 | 7.5 | 68.2 | 62 | 26 | 23 | 9 | 23 | 57 | 0 | 2 | 1 | 0 | 0 | 2 | 3 | 4.15 |