| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 13 | 13 | 8 | 2 | 2.43 | .245 | 0.96 | 6.9 | 1.7 | 9.3 | 96.1 | 74 | 26 | 26 | 7 | 18 | 99 | 1 | 0 | 0 | 0 | 12 | 2 | 1 | 2.51 |
| SP | Buehler, W.Buehler, Walker # >> | 23 | 2018 | R | 84 | 13 | 13 | 3 | 6 | 3.91 | .307 | 1.30 | 8.5 | 3.2 | 7.4 | 78.1 | 74 | 41 | 34 | 9 | 28 | 64 | 0 | 0 | 0 | 0 | 7 | 2 | 4 | 4.01 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 78 | 13 | 13 | 4 | 8 | 3.93 | .291 | 1.20 | 7.4 | 3.4 | 9.7 | 89.1 | 73 | 41 | 39 | 11 | 34 | 96 | 3 | 0 | 0 | 1 | 7 | 3 | 2 | 3.70 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 70 | 13 | 13 | 5 | 5 | 5.40 | .328 | 1.47 | 9.7 | 3.5 | 6.6 | 75.0 | 81 | 45 | 45 | 20 | 29 | 55 | 0 | 0 | 0 | 0 | 6 | 0 | 3 | 6.16 |
| SP | Hamels, C.Hamels, Cole >> | 28 | 2011 | L | 62 | 12 | 12 | 3 | 5 | 5.06 | .311 | 1.33 | 8.2 | 3.8 | 7.0 | 78.1 | 71 | 47 | 44 | 14 | 33 | 61 | 2 | 0 | 0 | 0 | 5 | 2 | 0 | 5.12 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 93 | 32 | 0 | 2 | 0 | 1.91 | .235 | 0.92 | 4.9 | 3.4 | 9.4 | 42.1 | 23 | 9 | 9 | 3 | 16 | 44 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2.98 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 68 | 28 | 0 | 4 | 0 | 1.85 | .266 | 1.03 | 6.4 | 2.9 | 10.1 | 34.0 | 24 | 8 | 7 | 2 | 11 | 38 | 0 | 2 | 0 | 0 | 0 | 2 | 2 | 2.68 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 64 | 8 | 0 | 0 | 0 | 4.00 | .206 | 0.78 | 4.0 | 3.0 | 7.0 | 9.0 | 4 | 4 | 4 | 3 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.78 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 69 | 2 | 0 | 0 | 0 | 0.00 | .308 | 1.00 | 3.0 | 6.0 | 9.0 | 3.0 | 1 | 0 | 0 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.00 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 63 | 4 | 0 | 0 | 1 | 11.57 | .462 | 2.57 | 18.0 | 9.0 | 0.0 | 2.1 | 4 | 5 | 3 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.00 |