| SP | Scherzer, M.Scherzer, Max $ >> | 33 | 2017 | R | 97 | 35 | 35 | 16 | 9 | 3.55 | .271 | 1.11 | 7.1 | 2.9 | 8.9 | 243.2 | 192 | 96 | 96 | 36 | 78 | 240 | 5 | 0 | 0 | 4 | 22 | 2 | 4 | 3.94 |
| SP | Nelson, R.Nelson, Roger $ >> | 28 | 1972 | R | 88 | 33 | 33 | 14 | 9 | 3.31 | .282 | 1.16 | 8.0 | 2.5 | 6.2 | 193.1 | 172 | 75 | 71 | 18 | 53 | 134 | 0 | 0 | 0 | 0 | 16 | 3 | 6 | 3.69 |
| SP | Gooden, D.Gooden, Dwight # $$ >> | 21 | 1985 | R | 78 | 32 | 32 | 14 | 15 | 4.56 | .320 | 1.39 | 9.2 | 3.3 | 6.3 | 246.2 | 252 | 127 | 125 | 32 | 90 | 171 | 11 | 0 | 0 | 1 | 16 | 7 | 13 | 4.48 |
| SP | Millwood, K.Millwood, Kevin # >> | 25 | 1999 | R | 70 | 31 | 31 | 13 | 13 | 5.31 | .316 | 1.37 | 8.9 | 3.5 | 6.7 | 190.0 | 187 | 117 | 112 | 51 | 73 | 142 | 1 | 0 | 0 | 1 | 13 | 3 | 3 | 6.19 |
| RP | Street, H.Street, Huston $ >> | 29 | 2012 | R | 95 | 97 | 0 | 3 | 6 | 2.45 | .241 | 0.93 | 5.1 | 3.3 | 8.7 | 132.1 | 75 | 38 | 36 | 12 | 48 | 127 | 0 | 13 | 5 | 0 | 0 | 3 | 1 | 3.42 |
| RP | Kuo, H.Kuo, Hong-Chih † >> | 29 | 2010 | L | 89 | 70 | 0 | 4 | 3 | 1.45 | .239 | 0.93 | 5.5 | 2.9 | 9.0 | 87.0 | 53 | 14 | 14 | 5 | 28 | 87 | 0 | 6 | 2 | 0 | 0 | 1 | 4 | 2.75 |
| RP | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 80 | 49 | 0 | 7 | 1 | 3.98 | .275 | 1.12 | 7.1 | 3.0 | 8.7 | 63.1 | 50 | 29 | 28 | 5 | 21 | 61 | 0 | 2 | 0 | 0 | 0 | 1 | 2 | 3.14 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 78 | 40 | 0 | 2 | 3 | 4.79 | .341 | 1.55 | 9.6 | 4.4 | 10.3 | 47.0 | 50 | 26 | 25 | 12 | 23 | 54 | 0 | 4 | 1 | 0 | 0 | 0 | 2 | 5.49 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 70 | 35 | 0 | 2 | 1 | 3.78 | .270 | 1.05 | 7.5 | 2.1 | 9.2 | 47.2 | 39 | 20 | 20 | 8 | 11 | 48 | 0 | 2 | 0 | 0 | 0 | 3 | 0 | 4.06 |