| SP | Arrieta, J.Arrieta, Jake $$ >> | 29 | 2015 | R | 95 | 34 | 34 | 9 | 19 | 5.41 | .334 | 1.47 | 9.9 | 3.4 | 9.0 | 209.2 | 231 | 132 | 126 | 29 | 78 | 209 | 0 | 0 | 0 | 0 | 14 | 7 | 10 | 4.02 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 78 | 32 | 32 | 8 | 13 | 5.29 | .351 | 1.58 | 10.6 | 3.6 | 9.1 | 192.1 | 227 | 117 | 113 | 41 | 77 | 194 | 1 | 0 | 0 | 1 | 15 | 8 | 4 | 5.08 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 70 | 32 | 32 | 12 | 15 | 5.91 | .363 | 1.65 | 10.7 | 4.2 | 6.8 | 207.0 | 245 | 144 | 136 | 37 | 97 | 156 | 7 | 0 | 0 | 0 | 13 | 12 | 5 | 5.40 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 84 | 31 | 31 | 13 | 14 | 4.46 | .317 | 1.36 | 8.9 | 3.4 | 7.0 | 200.0 | 197 | 105 | 99 | 23 | 75 | 156 | 8 | 0 | 0 | 1 | 18 | 7 | 2 | 4.17 |
| CL | Green, C.Green, Chad † >> | 26 | 2017 | R | 95 | 57 | 0 | 4 | 7 | 3.30 | .288 | 1.20 | 8.1 | 2.8 | 10.0 | 62.2 | 56 | 25 | 23 | 8 | 19 | 69 | 0 | 29 | 3 | 0 | 0 | 1 | 2 | 3.42 |
| SU | Papelbon, J.Papelbon, Jonathan $$ >> | 27 | 2007 | R | 91 | 69 | 0 | 0 | 1 | 4.86 | .301 | 1.28 | 7.7 | 3.9 | 10.3 | 79.2 | 68 | 43 | 43 | 12 | 34 | 90 | 0 | 7 | 5 | 0 | 0 | 1 | 0 | 4.03 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 53 | 0 | 2 | 1 | 2.88 | .282 | 1.16 | 7.6 | 2.9 | 10.7 | 59.1 | 50 | 23 | 19 | 5 | 19 | 70 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 2.75 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 73 | 45 | 0 | 3 | 0 | 3.43 | .307 | 1.28 | 8.1 | 3.5 | 10.1 | 60.1 | 54 | 25 | 23 | 2 | 23 | 67 | 0 | 0 | 0 | 0 | 0 | 3 | 10 | 2.50 |
| RP | Wetteland, J.Wetteland, John >> | 27 | 1993 | R | 39 | 41 | 0 | 4 | 0 | 2.32 | .276 | 1.07 | 5.3 | 4.3 | 8.7 | 54.1 | 32 | 14 | 14 | 7 | 26 | 52 | 0 | 0 | 0 | 0 | 0 | 4 | 4 | 4.43 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 66 | 4 | 0 | 0 | 0 | 4.76 | .370 | 1.41 | 10.8 | 3.6 | 5.4 | 5.2 | 6 | 3 | 3 | 2 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 9.40 |