| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 95 | 13 | 13 | 9 | 4 | 1.93 | .263 | 1.04 | 5.9 | 3.5 | 9.2 | 93.1 | 61 | 23 | 20 | 8 | 36 | 95 | 2 | 0 | 0 | 1 | 11 | 3 | 3 | 3.33 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 66 | 12 | 12 | 6 | 3 | 4.65 | .332 | 1.47 | 9.9 | 3.4 | 9.3 | 71.2 | 78 | 39 | 37 | 8 | 27 | 73 | 0 | 0 | 0 | 0 | 8 | 2 | 0 | 3.63 |
| CL | Doolittle, S.Doolittle, Sean $ >> | 31 | 2018 | L | 98 | 26 | 0 | 1 | 2 | 3.25 | .252 | 1.01 | 7.7 | 1.7 | 9.3 | 27.2 | 23 | 10 | 10 | 4 | 5 | 28 | 0 | 12 | 0 | 0 | 0 | 0 | 0 | 3.41 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 25 | 0 | 0 | 2 | 5.40 | .310 | 1.28 | 7.6 | 4.2 | 8.0 | 26.2 | 22 | 16 | 16 | 6 | 12 | 23 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 5.85 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 74 | 29 | 0 | 1 | 4 | 5.67 | .329 | 1.44 | 10.9 | 2.2 | 10.6 | 33.1 | 40 | 21 | 21 | 11 | 8 | 39 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 5.79 |
| RP | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 79 | 22 | 0 | 1 | 1 | 7.20 | .318 | 1.35 | 9.9 | 2.3 | 8.1 | 20.0 | 22 | 16 | 16 | 6 | 5 | 18 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 6.00 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 90 | 12 | 0 | 0 | 0 | 3.68 | .267 | 1.09 | 7.1 | 3.2 | 14.8 | 14.2 | 11 | 6 | 6 | 2 | 5 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.64 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 65 | 14 | 0 | 0 | 0 | 3.66 | .322 | 1.42 | 9.5 | 3.8 | 6.2 | 19.2 | 20 | 8 | 8 | 1 | 8 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.58 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 75 | 12 | 12 | 3 | 3 | 5.21 | .338 | 1.51 | 10.0 | 3.6 | 8.3 | 74.1 | 82 | 45 | 43 | 10 | 30 | 68 | 1 | 0 | 0 | 1 | 5 | 2 | 0 | 4.22 |