| SP | Arrieta, J.Arrieta, Jake $ >> | 29 | 2015 | R | 95 | 25 | 25 | 6 | 13 | 4.80 | .324 | 1.41 | 9.8 | 2.9 | 7.9 | 159.1 | 174 | 90 | 85 | 13 | 51 | 139 | 1 | 0 | 0 | 0 | 13 | 4 | 2 | 3.35 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 79 | 24 | 24 | 8 | 11 | 4.22 | .304 | 1.31 | 8.3 | 3.4 | 7.8 | 162.0 | 150 | 79 | 76 | 30 | 62 | 141 | 7 | 0 | 0 | 1 | 14 | 0 | 2 | 4.81 |
| SP | Perez, P.Perez, Pascual >> | 31 | 1988 | R | 77 | 24 | 24 | 6 | 14 | 6.32 | .359 | 1.64 | 10.7 | 4.1 | 5.9 | 131.0 | 156 | 98 | 92 | 28 | 59 | 86 | 1 | 0 | 0 | 0 | 10 | 5 | 4 | 5.93 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 72 | 24 | 24 | 7 | 10 | 5.43 | .329 | 1.43 | 9.1 | 3.9 | 6.8 | 142.2 | 143 | 86 | 86 | 28 | 61 | 107 | 3 | 0 | 0 | 0 | 11 | 6 | 3 | 5.47 |
| CL | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 59 | 0 | 2 | 7 | 2.97 | .261 | 1.03 | 6.5 | 2.9 | 9.5 | 72.2 | 52 | 24 | 24 | 10 | 23 | 76 | 0 | 27 | 2 | 0 | 0 | 2 | 0 | 3.74 |
| SU | Papelbon, J.Papelbon, Jonathan $ >> | 27 | 2007 | R | 91 | 53 | 0 | 2 | 0 | 2.97 | .239 | 0.93 | 5.7 | 2.7 | 11.9 | 63.2 | 40 | 25 | 21 | 4 | 19 | 83 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 2.14 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 79 | 65 | 0 | 7 | 1 | 2.03 | .250 | 0.98 | 5.7 | 3.0 | 8.8 | 80.0 | 51 | 18 | 18 | 5 | 27 | 78 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 2.95 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 74 | 45 | 0 | 5 | 1 | 3.02 | .289 | 1.13 | 7.1 | 3.2 | 11.4 | 56.2 | 44 | 20 | 19 | 7 | 20 | 71 | 0 | 6 | 1 | 0 | 0 | 5 | 2 | 3.43 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 64 | 46 | 0 | 4 | 1 | 4.78 | .300 | 1.27 | 9.2 | 2.3 | 8.4 | 58.1 | 59 | 31 | 31 | 7 | 15 | 54 | 0 | 2 | 0 | 0 | 0 | 1 | 5 | 3.53 |