| SP | deGrom, J.deGrom, Jacob # >> | 33 | 2021 | R | 100 | 10 | 10 | 3 | 2 | 3.14 | .244 | 0.92 | 6.7 | 1.6 | 10.1 | 63.0 | 47 | 24 | 22 | 6 | 11 | 71 | 0 | 0 | 0 | 0 | 8 | 3 | 0 | 2.65 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 87 | 10 | 10 | 2 | 5 | 5.37 | .325 | 1.39 | 9.0 | 3.6 | 9.6 | 60.1 | 60 | 37 | 36 | 14 | 24 | 64 | 1 | 0 | 0 | 0 | 5 | 3 | 2 | 5.25 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 78 | 9 | 9 | 1 | 6 | 5.81 | .352 | 1.61 | 10.9 | 3.8 | 8.1 | 52.2 | 63 | 35 | 34 | 11 | 22 | 47 | 0 | 0 | 0 | 0 | 2 | 1 | 3 | 5.27 |
| CL | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 87 | 19 | 0 | 1 | 1 | 1.04 | .250 | 1.00 | 4.2 | 4.8 | 9.3 | 26.0 | 12 | 5 | 3 | 1 | 14 | 27 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 3.04 |
| SU | Lidge, B.Lidge, Brad $ >> | 28 | 2004 | R | 60 | 18 | 0 | 0 | 0 | 5.49 | .289 | 1.22 | 7.6 | 3.8 | 10.4 | 19.2 | 16 | 12 | 12 | 4 | 8 | 22 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 4.68 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 76 | 28 | 0 | 0 | 1 | 4.58 | .329 | 1.47 | 9.5 | 4.2 | 10.6 | 17.2 | 18 | 9 | 9 | 2 | 8 | 20 | 0 | 1 | 0 | 0 | 0 | 0 | 5 | 3.59 |
| RP | Chapman, A.Chapman, Aroldis $$ >> | 24 | 2012 | L | 87 | 14 | 0 | 1 | 1 | 6.55 | .400 | 2.00 | 10.6 | 7.4 | 11.5 | 11.0 | 13 | 8 | 8 | 3 | 9 | 14 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 6.45 |
| RP | Gagne, E.Gagne, Eric $ >> | 27 | 2003 | R | 98 | 22 | 0 | 3 | 1 | 4.21 | .287 | 1.21 | 6.5 | 4.7 | 9.7 | 25.2 | 18 | 12 | 12 | 3 | 13 | 27 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 3.96 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 81 | 13 | 0 | 2 | 1 | 4.91 | .241 | 0.95 | 5.1 | 3.9 | 13.5 | 14.2 | 8 | 8 | 8 | 1 | 6 | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.21 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 55 | 10 | 0 | 1 | 0 | 3.06 | .281 | 1.18 | 7.9 | 2.8 | 9.0 | 32.1 | 28 | 14 | 11 | 6 | 10 | 32 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.38 |