| SP | Arrieta, J.Arrieta, Jake # >> | 29 | 2015 | R | 92 | 10 | 10 | 5 | 3 | 4.67 | .304 | 1.30 | 9.0 | 2.7 | 7.8 | 69.1 | 69 | 36 | 36 | 9 | 21 | 60 | 3 | 0 | 0 | 0 | 5 | 1 | 2 | 3.91 |
| SP | Mathewson, C.Mathewson, Christy $ >> | 28 | 1908 | R | 83 | 9 | 9 | 4 | 3 | 4.08 | .314 | 1.36 | 10.6 | 1.7 | 4.5 | 68.1 | 80 | 32 | 31 | 6 | 13 | 34 | 1 | 0 | 0 | 0 | 5 | 1 | 1 | 3.76 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 9 | 9 | 3 | 3 | 3.02 | .284 | 1.19 | 7.6 | 3.2 | 4.8 | 65.2 | 55 | 23 | 22 | 5 | 23 | 35 | 3 | 0 | 0 | 1 | 7 | 0 | 2 | 3.98 |
| RP | Kimbrel, C.Kimbrel, Craig $ >> | 24 | 2012 | R | 100 | 21 | 0 | 2 | 1 | 2.54 | .220 | 0.85 | 5.1 | 2.6 | 10.0 | 28.1 | 16 | 8 | 8 | 2 | 8 | 31 | 0 | 3 | 2 | 0 | 0 | 0 | 2 | 2.57 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 6 | 0 | 0 | 0 | 0.00 | .179 | 0.65 | 0.0 | 6.4 | 9.0 | 7.2 | 0 | 0 | 0 | 0 | 5 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.14 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 80 | 4 | 0 | 1 | 0 | 0.00 | .182 | 0.67 | 0.0 | 6.0 | 7.5 | 6.0 | 0 | 0 | 0 | 0 | 4 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.33 |