| SP | Tiant, L.Tiant, Luis † $$ >> | 28 | 1968 | R | 97 | 36 | 36 | 12 | 12 | 3.75 | .297 | 1.25 | 7.3 | 3.9 | 7.6 | 257.0 | 209 | 115 | 107 | 23 | 112 | 217 | 8 | 0 | 0 | 2 | 23 | 5 | 6 | 3.84 |
| SP | Arrieta, J.Arrieta, Jake # $$ >> | 29 | 2015 | R | 92 | 34 | 34 | 12 | 10 | 4.84 | .310 | 1.33 | 9.2 | 2.8 | 7.6 | 219.1 | 223 | 124 | 118 | 23 | 68 | 184 | 7 | 0 | 0 | 1 | 17 | 4 | 5 | 3.67 |
| SP | Mathewson, C.Mathewson, Christy $ >> | 28 | 1908 | R | 83 | 33 | 33 | 18 | 8 | 3.28 | .278 | 1.14 | 8.3 | 2.0 | 4.4 | 255.1 | 235 | 95 | 93 | 23 | 56 | 126 | 9 | 0 | 0 | 1 | 21 | 4 | 6 | 3.89 |
| SP | Horlen, J.Horlen, Joe # >> | 27 | 1964 | R | 78 | 33 | 33 | 16 | 10 | 4.27 | .287 | 1.19 | 7.8 | 2.9 | 4.9 | 219.1 | 191 | 107 | 104 | 22 | 71 | 120 | 3 | 0 | 0 | 1 | 20 | 3 | 4 | 4.22 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 31 | 31 | 15 | 11 | 3.38 | .299 | 1.27 | 7.8 | 3.6 | 5.3 | 228.2 | 198 | 88 | 86 | 22 | 92 | 135 | 8 | 0 | 0 | 2 | 20 | 3 | 4 | 4.32 |
| RP | Kimbrel, C.Kimbrel, Craig † $ >> | 24 | 2012 | R | 100 | 88 | 0 | 9 | 3 | 3.62 | .263 | 1.07 | 7.1 | 2.6 | 8.9 | 109.1 | 86 | 46 | 44 | 11 | 31 | 108 | 0 | 18 | 9 | 0 | 0 | 0 | 5 | 3.18 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 21 | 0 | 3 | 0 | 2.45 | .275 | 1.14 | 3.7 | 6.5 | 8.2 | 22.0 | 9 | 6 | 6 | 2 | 16 | 20 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 4.55 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 80 | 17 | 0 | 2 | 2 | 0.95 | .230 | 0.89 | 4.7 | 3.3 | 8.5 | 19.0 | 10 | 3 | 2 | 1 | 7 | 18 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2.89 |