| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 24 | 24 | 7 | 15 | 5.03 | .326 | 1.43 | 9.1 | 3.8 | 8.1 | 152.0 | 153 | 87 | 85 | 24 | 65 | 137 | 3 | 0 | 0 | 1 | 13 | 3 | 2 | 4.59 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 22 | 22 | 10 | 7 | 4.17 | .287 | 1.17 | 8.1 | 2.4 | 4.5 | 151.0 | 136 | 71 | 70 | 23 | 41 | 76 | 6 | 0 | 0 | 2 | 14 | 5 | 4 | 4.89 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 22 | 22 | 7 | 12 | 5.60 | .332 | 1.46 | 10.6 | 2.6 | 5.2 | 141.1 | 166 | 92 | 88 | 22 | 41 | 82 | 6 | 0 | 0 | 0 | 8 | 4 | 5 | 4.82 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 21 | 21 | 8 | 7 | 4.38 | .327 | 1.45 | 8.9 | 4.1 | 5.7 | 127.1 | 126 | 66 | 62 | 12 | 58 | 81 | 1 | 0 | 0 | 1 | 10 | 2 | 2 | 4.37 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 57 | 0 | 2 | 2 | 2.64 | .277 | 1.15 | 7.4 | 3.0 | 8.8 | 81.2 | 67 | 26 | 24 | 7 | 27 | 79 | 0 | 8 | 1 | 0 | 0 | 0 | 0 | 3.17 |
| RP | Zimmerman, J.Zimmerman, Jeff † >> | 27 | 1999 | R | 70 | 55 | 0 | 1 | 2 | 1.77 | .232 | 0.88 | 5.2 | 2.7 | 5.3 | 76.1 | 44 | 16 | 15 | 6 | 23 | 45 | 0 | 9 | 4 | 0 | 0 | 2 | 1 | 3.83 |
| RP | Hernandez, W.Hernandez, Willie >> | 30 | 1984 | L | 44 | 20 | 0 | 0 | 1 | 3.00 | .250 | 0.93 | 8.0 | 0.3 | 5.0 | 27.0 | 24 | 10 | 9 | 2 | 1 | 15 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 3.19 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 3 | 1 | 1 | 0 | 4.76 | .370 | 1.76 | 12.3 | 4.1 | 5.7 | 11.1 | 15 | 8 | 6 | 2 | 5 | 7 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 5.45 |
| SP | Russell, R.Russell, Reb >> | 27 | 1916 | L | 52 | 7 | 0 | 1 | 0 | 3.48 | .279 | 1.16 | 9.0 | 1.8 | 3.6 | 10.1 | 10 | 4 | 4 | 2 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.40 |