| SP | Arrieta, J.Arrieta, Jake $ >> | 29 | 2015 | R | 93 | 29 | 29 | 12 | 6 | 3.15 | .277 | 1.13 | 7.3 | 2.9 | 7.5 | 177.1 | 143 | 63 | 62 | 20 | 58 | 147 | 2 | 0 | 0 | 0 | 21 | 3 | 2 | 3.84 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 28 | 28 | 13 | 5 | 3.01 | .246 | 0.98 | 6.3 | 2.5 | 4.5 | 188.2 | 132 | 64 | 63 | 13 | 52 | 95 | 2 | 0 | 0 | 1 | 21 | 1 | 2 | 3.73 |
| SP | Ryan, N.Ryan, Nolan # $$ >> | 44 | 1991 | R | 73 | 27 | 27 | 11 | 10 | 4.05 | .282 | 1.17 | 6.3 | 4.2 | 6.8 | 169.0 | 119 | 79 | 76 | 16 | 79 | 127 | 3 | 0 | 0 | 1 | 15 | 1 | 4 | 4.15 |
| SP | McDowell, S.McDowell, Sam >> | 26 | 1968 | L | 45 | 25 | 25 | 9 | 9 | 5.14 | .320 | 1.38 | 8.6 | 3.9 | 7.2 | 161.0 | 153 | 95 | 92 | 20 | 69 | 128 | 6 | 0 | 0 | 0 | 12 | 5 | 3 | 4.40 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 73 | 0 | 7 | 5 | 1.97 | .253 | 1.00 | 5.7 | 3.3 | 9.4 | 105.1 | 66 | 24 | 23 | 9 | 39 | 110 | 0 | 10 | 6 | 0 | 0 | 2 | 5 | 3.19 |
| RP | Kuo, H.Kuo, Hong-Chih † >> | 29 | 2010 | L | 90 | 66 | 0 | 7 | 4 | 2.27 | .259 | 1.04 | 5.4 | 4.0 | 7.6 | 75.1 | 45 | 20 | 19 | 3 | 33 | 63 | 0 | 11 | 2 | 0 | 0 | 1 | 8 | 3.20 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 47 | 0 | 3 | 5 | 3.36 | .302 | 1.28 | 8.8 | 2.7 | 7.9 | 56.1 | 55 | 21 | 21 | 0 | 17 | 49 | 0 | 6 | 4 | 0 | 0 | 1 | 0 | 2.21 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 22 | 0 | 3 | 1 | 3.20 | .303 | 1.30 | 6.5 | 5.4 | 7.2 | 25.1 | 18 | 9 | 9 | 3 | 15 | 20 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 4.76 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 48 | 29 | 0 | 5 | 0 | 4.30 | .302 | 1.30 | 6.8 | 4.9 | 7.6 | 73.1 | 55 | 36 | 35 | 7 | 40 | 62 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 4.19 |