| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 24 | 24 | 11 | 6 | 3.01 | .269 | 1.08 | 7.1 | 2.7 | 7.1 | 158.2 | 124 | 54 | 53 | 18 | 47 | 124 | 1 | 0 | 0 | 0 | 17 | 4 | 3 | 3.88 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 23 | 23 | 12 | 8 | 2.91 | .252 | 0.99 | 6.6 | 2.3 | 4.9 | 158.0 | 115 | 52 | 51 | 8 | 41 | 86 | 2 | 0 | 0 | 1 | 15 | 4 | 1 | 3.42 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 22 | 22 | 11 | 4 | 4.08 | .297 | 1.25 | 8.2 | 3.0 | 6.3 | 128.0 | 117 | 59 | 58 | 16 | 43 | 90 | 2 | 0 | 0 | 0 | 15 | 2 | 1 | 4.27 |
| SP | McDowell, S.McDowell, Sam # >> | 26 | 1968 | L | 45 | 21 | 21 | 9 | 4 | 3.92 | .280 | 1.15 | 7.5 | 3.0 | 6.8 | 137.2 | 114 | 60 | 60 | 15 | 45 | 104 | 2 | 0 | 0 | 1 | 12 | 2 | 4 | 3.93 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 61 | 0 | 4 | 2 | 2.13 | .266 | 1.07 | 5.7 | 4.1 | 9.9 | 84.2 | 53 | 21 | 20 | 5 | 38 | 92 | 0 | 8 | 2 | 0 | 0 | 1 | 0 | 2.98 |
| RP | Miller, A.Miller, Andrew † >> | 29 | 2014 | L | 88 | 52 | 0 | 8 | 4 | 3.05 | .288 | 1.20 | 8.0 | 2.7 | 9.3 | 56.0 | 50 | 20 | 19 | 7 | 17 | 58 | 0 | 10 | 4 | 0 | 0 | 1 | 1 | 3.52 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 26 | 0 | 3 | 1 | 2.84 | .286 | 1.20 | 6.7 | 4.4 | 7.5 | 31.2 | 23 | 10 | 10 | 2 | 15 | 26 | 0 | 4 | 1 | 0 | 0 | 0 | 1 | 3.61 |
| RP | Radatz, D.Radatz, Dick >> | 27 | 1964 | R | 37 | 8 | 0 | 0 | 1 | 4.60 | .329 | 1.40 | 6.6 | 6.6 | 9.0 | 15.2 | 11 | 8 | 8 | 1 | 11 | 15 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.27 |