| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 32 | 32 | 14 | 8 | 3.73 | .278 | 1.14 | 7.9 | 2.4 | 10.0 | 215.0 | 188 | 95 | 89 | 28 | 58 | 238 | 1 | 0 | 0 | 0 | 21 | 2 | 0 | 3.32 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 81 | 33 | 33 | 12 | 20 | 5.76 | .349 | 1.59 | 10.7 | 3.6 | 5.5 | 217.1 | 259 | 147 | 139 | 35 | 86 | 132 | 3 | 0 | 0 | 0 | 15 | 5 | 3 | 5.14 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 32 | 32 | 9 | 17 | 5.22 | .336 | 1.51 | 10.4 | 3.1 | 4.0 | 224.1 | 260 | 135 | 130 | 30 | 78 | 99 | 4 | 0 | 0 | 1 | 10 | 3 | 8 | 4.94 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 31 | 31 | 11 | 11 | 5.22 | .341 | 1.53 | 10.6 | 3.2 | 4.8 | 207.0 | 243 | 126 | 120 | 17 | 74 | 110 | 1 | 0 | 0 | 0 | 13 | 5 | 5 | 4.15 |
| CL | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 95 | 55 | 0 | 1 | 4 | 2.42 | .243 | 0.96 | 5.6 | 3.1 | 9.6 | 63.1 | 39 | 19 | 17 | 4 | 22 | 67 | 0 | 37 | 5 | 0 | 0 | 0 | 0 | 2.75 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 88 | 0 | 6 | 6 | 3.90 | .289 | 1.21 | 9.3 | 1.6 | 7.9 | 97.0 | 100 | 44 | 42 | 11 | 17 | 85 | 0 | 3 | 5 | 0 | 0 | 1 | 0 | 3.28 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 74 | 0 | 4 | 5 | 5.55 | .327 | 1.44 | 10.1 | 2.9 | 9.3 | 71.1 | 80 | 46 | 44 | 17 | 23 | 73 | 0 | 2 | 3 | 0 | 0 | 1 | 5 | 5.07 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 57 | 0 | 2 | 1 | 1.57 | .247 | 0.99 | 5.6 | 3.3 | 8.5 | 69.0 | 43 | 14 | 12 | 4 | 25 | 65 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.96 |