| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 8 | 8 | 2 | 2 | 5.04 | .318 | 1.38 | 8.6 | 3.8 | 9.9 | 50.0 | 48 | 28 | 28 | 8 | 21 | 55 | 0 | 0 | 0 | 0 | 4 | 1 | 0 | 4.20 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 10 | 10 | 0 | 10 | 8.40 | .398 | 1.95 | 12.8 | 4.8 | 5.7 | 60.0 | 85 | 58 | 56 | 10 | 32 | 38 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 5.60 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 9 | 9 | 3 | 3 | 4.45 | .338 | 1.52 | 10.5 | 3.3 | 5.2 | 62.2 | 72 | 32 | 31 | 4 | 23 | 36 | 1 | 0 | 0 | 1 | 4 | 1 | 2 | 3.84 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 9 | 9 | 4 | 3 | 4.79 | .329 | 1.44 | 10.2 | 2.8 | 4.1 | 62.0 | 70 | 37 | 33 | 5 | 19 | 28 | 1 | 0 | 0 | 0 | 4 | 2 | 2 | 4.16 |
| CL | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 15 | 0 | 1 | 1 | 2.00 | .217 | 0.83 | 3.0 | 4.5 | 10.5 | 18.0 | 6 | 4 | 4 | 0 | 9 | 21 | 0 | 9 | 0 | 0 | 0 | 0 | 0 | 2.17 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 27 | 0 | 2 | 2 | 3.86 | .294 | 1.25 | 10.0 | 1.3 | 7.7 | 28.0 | 31 | 13 | 12 | 6 | 4 | 24 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 4.50 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 22 | 0 | 2 | 0 | 7.71 | .320 | 1.41 | 11.3 | 1.6 | 8.2 | 23.1 | 29 | 21 | 20 | 9 | 4 | 21 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 6.78 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 16 | 0 | 1 | 0 | 2.37 | .269 | 1.11 | 7.1 | 2.8 | 8.5 | 19.0 | 15 | 6 | 5 | 3 | 6 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.11 |