| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 34 | 34 | 11 | 10 | 4.50 | .299 | 1.25 | 8.3 | 2.9 | 8.5 | 232.0 | 214 | 117 | 116 | 27 | 76 | 219 | 0 | 0 | 0 | 0 | 17 | 7 | 8 | 3.70 |
| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 33 | 33 | 12 | 9 | 4.69 | .296 | 1.25 | 8.9 | 2.4 | 4.5 | 180.1 | 178 | 101 | 94 | 14 | 47 | 89 | 0 | 0 | 0 | 0 | 15 | 3 | 4 | 3.86 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 31 | 31 | 10 | 15 | 4.76 | .308 | 1.33 | 9.7 | 2.3 | 4.6 | 226.2 | 243 | 130 | 120 | 33 | 58 | 116 | 9 | 0 | 0 | 2 | 11 | 2 | 7 | 4.67 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 85 | 0 | 4 | 6 | 2.83 | .276 | 1.13 | 6.7 | 3.5 | 7.4 | 114.1 | 85 | 36 | 36 | 8 | 44 | 94 | 0 | 6 | 11 | 0 | 0 | 2 | 6 | 3.47 |
| RP | Soria, J.Soria, Joakim † >> | 24 | 2008 | R | 68 | 78 | 0 | 5 | 3 | 2.43 | .253 | 1.00 | 5.4 | 3.6 | 5.4 | 111.1 | 66 | 30 | 30 | 7 | 45 | 66 | 0 | 12 | 3 | 0 | 0 | 2 | 2 | 3.90 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 60 | 74 | 0 | 7 | 5 | 3.78 | .281 | 1.15 | 7.7 | 2.7 | 7.6 | 81.0 | 69 | 35 | 34 | 9 | 24 | 68 | 0 | 7 | 5 | 0 | 0 | 2 | 1 | 3.73 |
| RP | Rincon, J.Rincon, Juan >> | 25 | 2004 | R | 45 | 38 | 0 | 2 | 3 | 4.50 | .326 | 1.45 | 8.6 | 4.5 | 9.0 | 42.0 | 40 | 22 | 21 | 7 | 21 | 42 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 4.67 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 52 | 3 | 0 | 1 | 0 | 3.86 | .300 | 1.29 | 9.0 | 2.6 | 2.6 | 7.0 | 7 | 3 | 3 | 1 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.14 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 14 | 0 | 3 | 3 | 2.60 | .283 | 1.18 | 8.2 | 2.6 | 7.4 | 34.2 | 31 | 10 | 10 | 4 | 10 | 28 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.76 |