| SP | deGrom, J.deGrom, Jacob # $ >> | 33 | 2021 | R | 100 | 24 | 24 | 7 | 9 | 3.39 | .281 | 1.14 | 7.7 | 2.6 | 10.3 | 148.2 | 127 | 61 | 56 | 20 | 43 | 170 | 0 | 0 | 0 | 0 | 16 | 4 | 0 | 3.41 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 22 | 22 | 6 | 7 | 6.64 | .345 | 1.56 | 10.7 | 3.4 | 8.2 | 107.0 | 127 | 83 | 79 | 17 | 40 | 97 | 0 | 0 | 0 | 0 | 8 | 2 | 6 | 4.43 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 23 | 22 | 10 | 7 | 4.64 | .314 | 1.36 | 9.7 | 2.6 | 6.0 | 143.2 | 154 | 74 | 74 | 25 | 41 | 95 | 5 | 1 | 0 | 1 | 10 | 2 | 3 | 4.85 |
| CL | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 61 | 0 | 5 | 14 | 6.84 | .330 | 1.48 | 8.0 | 5.3 | 8.3 | 75.0 | 67 | 57 | 57 | 15 | 44 | 69 | 0 | 19 | 7 | 0 | 0 | 0 | 0 | 5.52 |
| SU | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 60 | 0 | 4 | 0 | 3.32 | .291 | 1.22 | 8.6 | 2.4 | 7.5 | 65.0 | 62 | 26 | 24 | 3 | 17 | 54 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 2.77 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 55 | 0 | 4 | 3 | 4.31 | .338 | 1.53 | 8.7 | 5.2 | 5.8 | 64.2 | 62 | 33 | 31 | 9 | 37 | 41 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 5.28 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 53 | 0 | 5 | 1 | 4.95 | .311 | 1.34 | 9.0 | 3.1 | 8.6 | 67.1 | 67 | 37 | 37 | 6 | 23 | 64 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.33 |