| SP | Martinez, P.Martinez, Pedro # >> | 29 | 2000 | R | 100 | 29 | 29 | 14 | 9 | 3.55 | .277 | 1.12 | 7.9 | 2.2 | 9.0 | 228.0 | 201 | 92 | 90 | 22 | 55 | 227 | 9 | 0 | 0 | 0 | 19 | 6 | 4 | 3.07 |
| SP | Nelson, R.Nelson, Roger # >> | 28 | 1972 | R | 84 | 28 | 28 | 10 | 10 | 5.00 | .317 | 1.38 | 8.6 | 3.9 | 4.3 | 147.2 | 141 | 92 | 82 | 21 | 63 | 70 | 0 | 0 | 0 | 0 | 8 | 2 | 4 | 5.23 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 28 | 28 | 13 | 10 | 4.90 | .314 | 1.36 | 9.0 | 3.3 | 6.4 | 205.2 | 204 | 114 | 112 | 33 | 75 | 145 | 7 | 0 | 0 | 0 | 12 | 4 | 10 | 4.83 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 27 | 27 | 8 | 12 | 6.01 | .363 | 1.67 | 10.1 | 5.0 | 5.2 | 169.1 | 189 | 121 | 113 | 24 | 93 | 98 | 0 | 0 | 0 | 0 | 8 | 7 | 6 | 5.46 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 63 | 0 | 6 | 2 | 3.19 | .302 | 1.26 | 8.8 | 2.7 | 8.8 | 84.2 | 82 | 31 | 30 | 5 | 25 | 82 | 0 | 5 | 0 | 0 | 0 | 3 | 1 | 2.82 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 53 | 0 | 4 | 1 | 3.66 | .292 | 1.23 | 8.3 | 2.8 | 8.4 | 64.0 | 59 | 28 | 26 | 9 | 20 | 60 | 0 | 9 | 1 | 0 | 0 | 0 | 0 | 3.89 |
| RP | Niedenfuer, T.Niedenfuer, Tom >> | 24 | 1983 | R | 61 | 32 | 0 | 3 | 4 | 3.93 | .290 | 1.23 | 7.3 | 4.0 | 5.8 | 36.2 | 29 | 16 | 16 | 3 | 16 | 23 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.14 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 53 | 30 | 0 | 0 | 0 | 4.14 | .315 | 1.34 | 7.6 | 4.6 | 7.8 | 45.2 | 38 | 21 | 21 | 6 | 23 | 39 | 0 | 2 | 0 | 0 | 0 | 2 | 0 | 4.67 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 59 | 9 | 0 | 3 | 1 | 3.93 | .353 | 1.64 | 8.5 | 6.5 | 9.0 | 18.1 | 17 | 8 | 8 | 1 | 13 | 18 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.89 |