| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 37 | 37 | 17 | 11 | 2.52 | .248 | 0.98 | 6.6 | 2.2 | 8.6 | 250.0 | 182 | 74 | 70 | 23 | 62 | 240 | 3 | 0 | 0 | 2 | 26 | 4 | 0 | 3.07 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 36 | 36 | 18 | 12 | 3.35 | .275 | 1.11 | 8.2 | 1.7 | 5.5 | 247.0 | 226 | 96 | 92 | 27 | 48 | 151 | 7 | 0 | 0 | 1 | 22 | 7 | 3 | 3.87 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 34 | 34 | 19 | 8 | 3.41 | .269 | 1.08 | 7.3 | 2.4 | 8.5 | 237.2 | 193 | 93 | 90 | 23 | 63 | 224 | 14 | 0 | 0 | 4 | 21 | 6 | 3 | 3.24 |
| RP | Doolittle, S.Doolittle, Sean $ >> | 31 | 2018 | L | 99 | 82 | 0 | 7 | 1 | 2.59 | .234 | 0.92 | 7.0 | 1.3 | 7.9 | 90.1 | 70 | 27 | 26 | 7 | 13 | 79 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 2.69 |
| RP | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 91 | 74 | 0 | 4 | 2 | 1.80 | .236 | 0.93 | 5.8 | 2.6 | 11.8 | 70.0 | 45 | 14 | 14 | 7 | 20 | 92 | 0 | 1 | 3 | 0 | 0 | 0 | 2 | 2.53 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 55 | 0 | 2 | 1 | 3.34 | .271 | 1.09 | 4.6 | 5.1 | 9.8 | 35.0 | 18 | 13 | 13 | 6 | 20 | 38 | 0 | 3 | 1 | 0 | 0 | 1 | 2 | 4.86 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 82 | 28 | 0 | 5 | 1 | 2.61 | .301 | 1.26 | 6.4 | 4.9 | 6.1 | 31.0 | 22 | 9 | 9 | 0 | 17 | 21 | 0 | 3 | 1 | 0 | 0 | 1 | 1 | 3.39 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 32 | 31 | 13 | 11 | 4.14 | .305 | 1.30 | 9.0 | 2.7 | 5.4 | 215.1 | 215 | 106 | 99 | 30 | 64 | 129 | 13 | 0 | 0 | 1 | 15 | 5 | 5 | 4.58 |