| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 22 | 22 | 6 | 13 | 4.58 | .304 | 1.30 | 8.5 | 3.3 | 8.1 | 155.1 | 146 | 82 | 79 | 17 | 56 | 139 | 3 | 0 | 0 | 0 | 10 | 2 | 3 | 3.75 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 21 | 21 | 5 | 10 | 4.78 | .320 | 1.39 | 9.8 | 2.8 | 7.7 | 152.2 | 165 | 86 | 81 | 15 | 47 | 130 | 3 | 0 | 0 | 0 | 9 | 4 | 7 | 3.58 |
| SP | Krause, H.Krause, Harry # >> | 21 | 1909 | L | 72 | 20 | 20 | 5 | 9 | 5.71 | .324 | 1.38 | 10.3 | 2.2 | 5.0 | 115.0 | 131 | 83 | 73 | 18 | 28 | 64 | 0 | 0 | 0 | 0 | 7 | 6 | 2 | 4.81 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 20 | 20 | 10 | 7 | 4.46 | .319 | 1.39 | 9.1 | 3.5 | 4.3 | 143.1 | 144 | 77 | 71 | 8 | 55 | 69 | 4 | 0 | 0 | 0 | 11 | 2 | 1 | 3.96 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 19 | 19 | 4 | 8 | 5.94 | .378 | 1.80 | 9.9 | 6.3 | 3.9 | 103.0 | 113 | 74 | 68 | 9 | 72 | 45 | 0 | 0 | 0 | 0 | 5 | 3 | 2 | 5.45 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 53 | 0 | 0 | 4 | 5.05 | .329 | 1.47 | 9.4 | 3.8 | 9.0 | 66.0 | 69 | 40 | 37 | 8 | 28 | 66 | 0 | 1 | 4 | 0 | 0 | 0 | 4 | 3.85 |
| RP | Zimmerman, J.Zimmerman, Jeff † >> | 27 | 1999 | R | 70 | 54 | 0 | 8 | 1 | 3.31 | .252 | 1.01 | 5.8 | 3.3 | 4.6 | 73.1 | 47 | 30 | 27 | 10 | 27 | 37 | 0 | 10 | 2 | 0 | 0 | 0 | 1 | 4.88 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 33 | 0 | 2 | 3 | 4.70 | .358 | 1.64 | 6.2 | 8.8 | 7.8 | 38.1 | 26 | 20 | 20 | 7 | 37 | 33 | 0 | 1 | 3 | 0 | 0 | 1 | 1 | 6.66 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 57 | 25 | 0 | 0 | 1 | 5.11 | .357 | 1.66 | 9.8 | 5.6 | 9.4 | 24.2 | 26 | 15 | 14 | 3 | 15 | 25 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.42 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 51 | 29 | 0 | 1 | 2 | 4.35 | .340 | 1.55 | 12.2 | 1.7 | 8.4 | 31.0 | 42 | 16 | 15 | 3 | 6 | 29 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 2.97 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 11 | 1 | 4 | 0 | 3.20 | .296 | 1.22 | 7.6 | 3.6 | 4.3 | 25.1 | 21 | 11 | 9 | 2 | 10 | 12 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 4.40 |