| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 10 | 10 | 5 | 3 | 3.61 | .295 | 1.24 | 7.4 | 3.9 | 7.9 | 77.1 | 63 | 35 | 31 | 5 | 33 | 68 | 2 | 0 | 0 | 2 | 5 | 1 | 3 | 3.40 |
| SP | Hernandez, F.Hernandez, Felix # >> | 28 | 2014 | R | 80 | 10 | 10 | 3 | 5 | 4.26 | .302 | 1.27 | 8.3 | 3.2 | 7.7 | 67.2 | 62 | 39 | 32 | 7 | 24 | 57 | 0 | 0 | 0 | 0 | 6 | 2 | 0 | 3.82 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 10 | 10 | 2 | 8 | 5.72 | .348 | 1.58 | 11.7 | 2.7 | 6.6 | 61.1 | 79 | 45 | 39 | 14 | 18 | 45 | 1 | 0 | 0 | 0 | 4 | 1 | 0 | 5.44 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 69 | 9 | 9 | 4 | 5 | 3.82 | .309 | 1.34 | 9.3 | 3.0 | 5.1 | 70.2 | 72 | 33 | 30 | 5 | 23 | 40 | 5 | 0 | 0 | 0 | 4 | 0 | 2 | 3.77 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 22 | 0 | 1 | 2 | 5.61 | .342 | 1.56 | 11.2 | 3.2 | 8.3 | 25.2 | 31 | 19 | 16 | 4 | 9 | 23 | 0 | 5 | 1 | 0 | 0 | 0 | 1 | 4.32 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 15 | 0 | 0 | 0 | 3.86 | .354 | 1.64 | 7.7 | 7.1 | 7.1 | 14.0 | 12 | 6 | 6 | 1 | 11 | 11 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 4.71 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 7 | 0 | 1 | 1 | 5.00 | .386 | 1.89 | 13.0 | 4.0 | 8.0 | 9.0 | 13 | 5 | 5 | 2 | 4 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.44 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 13 | 0 | 0 | 0 | 3.63 | .325 | 1.44 | 7.4 | 5.8 | 5.3 | 17.1 | 14 | 7 | 7 | 3 | 11 | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 6.06 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 65 | 3 | 0 | 0 | 0 | 1.35 | .200 | 0.75 | 6.0 | 1.5 | 1.5 | 6.2 | 4 | 2 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.17 |