| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 13 | 13 | 4 | 3 | 2.97 | .242 | 0.93 | 6.7 | 1.7 | 6.3 | 91.0 | 68 | 30 | 30 | 11 | 17 | 64 | 1 | 0 | 0 | 0 | 10 | 2 | 0 | 3.79 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 12 | 12 | 8 | 0 | 2.28 | .248 | 0.98 | 6.2 | 2.6 | 6.8 | 83.0 | 57 | 21 | 21 | 7 | 24 | 63 | 0 | 0 | 0 | 0 | 10 | 1 | 3 | 3.48 |
| SP | Lundgren, C.Lundgren, Carl $$ >> | 27 | 1907 | R | 43 | 12 | 12 | 5 | 1 | 2.28 | .229 | 0.89 | 5.3 | 2.8 | 3.6 | 75.0 | 44 | 19 | 19 | 4 | 23 | 30 | 0 | 0 | 0 | 0 | 8 | 0 | 0 | 3.81 |
| SP | Reulbach, E.Reulbach, Ed $$ >> | 24 | 1906 | R | 60 | 12 | 12 | 6 | 1 | 2.74 | .278 | 1.13 | 6.5 | 3.7 | 4.7 | 65.2 | 47 | 24 | 20 | 5 | 27 | 34 | 0 | 0 | 0 | 0 | 5 | 2 | 0 | 4.29 |
| CL | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 98 | 33 | 0 | 5 | 3 | 1.86 | .247 | 0.98 | 5.9 | 3.1 | 5.7 | 38.2 | 25 | 9 | 8 | 2 | 13 | 24 | 0 | 23 | 1 | 0 | 0 | 0 | 0 | 3.45 |
| SU | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 92 | 26 | 0 | 0 | 4 | 4.74 | .308 | 1.30 | 9.8 | 2.3 | 9.8 | 24.2 | 26 | 13 | 13 | 4 | 6 | 26 | 0 | 3 | 3 | 0 | 0 | 1 | 1 | 3.88 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 22 | 0 | 1 | 3 | 3.46 | .264 | 1.00 | 7.3 | 1.7 | 7.6 | 26.0 | 21 | 11 | 10 | 5 | 5 | 22 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 4.62 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 12 | 0 | 0 | 0 | 1.88 | .218 | 0.84 | 5.8 | 1.9 | 14.1 | 14.1 | 9 | 3 | 3 | 0 | 3 | 22 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0.50 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 10 | 0 | 2 | 0 | 1.69 | .238 | 0.94 | 7.2 | 1.8 | 10.8 | 10.2 | 8 | 2 | 2 | 1 | 2 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.50 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 4 | 0 | 0 | 0 | 1.59 | .227 | 0.88 | 3.6 | 5.4 | 9.0 | 5.2 | 2 | 1 | 1 | 1 | 3 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.40 |
| SP | McDowell, S.McDowell, Sam >> | 23 | 1965 | L | 44 | 5 | 0 | 4 | 0 | 0.89 | .197 | 0.69 | 3.6 | 2.7 | 6.3 | 20.1 | 8 | 2 | 2 | 1 | 6 | 14 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.30 |