| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 13 | 13 | 6 | 2 | 4.89 | .275 | 1.11 | 7.9 | 2.1 | 9.0 | 77.1 | 68 | 42 | 42 | 15 | 18 | 77 | 1 | 0 | 0 | 0 | 8 | 2 | 1 | 4.31 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 12 | 12 | 3 | 4 | 4.15 | .308 | 1.31 | 8.9 | 3.0 | 4.2 | 82.1 | 81 | 40 | 38 | 7 | 27 | 38 | 1 | 0 | 0 | 0 | 6 | 2 | 0 | 4.24 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 77 | 12 | 12 | 6 | 4 | 3.63 | .291 | 1.22 | 8.7 | 2.3 | 6.0 | 89.1 | 86 | 40 | 36 | 12 | 23 | 59 | 4 | 0 | 0 | 1 | 6 | 1 | 1 | 4.24 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 12 | 12 | 1 | 7 | 7.23 | .394 | 1.88 | 11.7 | 5.1 | 4.3 | 56.0 | 73 | 47 | 45 | 16 | 32 | 27 | 0 | 0 | 0 | 0 | 2 | 4 | 1 | 7.68 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 34 | 0 | 0 | 2 | 3.41 | .264 | 1.04 | 6.1 | 3.5 | 8.7 | 31.2 | 21 | 13 | 12 | 3 | 12 | 30 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.58 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 35 | 0 | 1 | 3 | 5.40 | .371 | 1.71 | 11.3 | 4.1 | 9.3 | 35.0 | 44 | 23 | 21 | 5 | 16 | 36 | 0 | 1 | 1 | 0 | 0 | 2 | 3 | 4.34 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 28 | 0 | 2 | 3 | 4.06 | .306 | 1.29 | 7.8 | 3.8 | 5.5 | 31.0 | 27 | 15 | 14 | 5 | 13 | 19 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5.23 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 1 | 0 | 0 | 0 | 13.50 | .500 | 3.00 | 27.0 | 9.0 | 18.0 | 1.1 | 3 | 2 | 2 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.00 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 3 | 0 | 1 | 0 | 7.11 | .472 | 2.68 | 18.0 | 7.5 | 10.5 | 6.1 | 12 | 5 | 5 | 1 | 5 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.33 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 17 | 0 | 1 | 2 | 5.68 | .315 | 1.38 | 7.2 | 5.4 | 7.9 | 25.1 | 20 | 16 | 16 | 3 | 15 | 22 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 4.60 |