| SP | Leonard, D.Leonard, Dutch $$ >> | 22 | 1914 | L | 91 | 14 | 14 | 6 | 3 | 3.12 | .292 | 1.21 | 6.9 | 4.0 | 6.5 | 92.1 | 71 | 35 | 32 | 9 | 41 | 66 | 0 | 0 | 0 | 0 | 9 | 2 | 0 | 4.24 |
| SP | Kershaw, C.Kershaw, Clayton $$ >> | 28 | 2016 | L | 99 | 13 | 13 | 5 | 7 | 3.49 | .301 | 1.25 | 9.5 | 1.8 | 7.6 | 95.1 | 100 | 39 | 37 | 8 | 19 | 80 | 2 | 0 | 0 | 1 | 9 | 4 | 2 | 3.14 |
| SP | McLain, D.McLain, Denny # >> | 24 | 1968 | R | 78 | 14 | 12 | 6 | 6 | 4.67 | .281 | 1.14 | 7.8 | 2.6 | 5.9 | 88.2 | 76 | 46 | 46 | 11 | 25 | 58 | 1 | 0 | 0 | 0 | 5 | 3 | 1 | 4.26 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 12 | 12 | 4 | 4 | 3.93 | .324 | 1.41 | 10.0 | 2.9 | 4.9 | 75.2 | 83 | 38 | 33 | 9 | 24 | 41 | 0 | 0 | 0 | 0 | 6 | 2 | 1 | 4.51 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 84 | 13 | 13 | 5 | 8 | 4.93 | .327 | 1.46 | 10.9 | 2.4 | 4.8 | 87.2 | 105 | 54 | 48 | 10 | 23 | 46 | 1 | 0 | 0 | 0 | 6 | 0 | 2 | 4.23 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 30 | 0 | 4 | 0 | 2.81 | .222 | 0.86 | 6.8 | 1.1 | 8.6 | 25.2 | 19 | 9 | 8 | 3 | 3 | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 28 | 0 | 1 | 2 | 3.09 | .304 | 1.31 | 9.0 | 2.8 | 8.2 | 32.0 | 32 | 11 | 11 | 4 | 10 | 29 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 3.75 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 9 | 0 | 0 | 0 | 5.91 | .360 | 1.59 | 10.8 | 4.5 | 9.0 | 10.2 | 12 | 7 | 7 | 3 | 5 | 10 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 6.70 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 6 | 3 | 1 | 1 | 6.23 | .339 | 1.50 | 8.3 | 5.2 | 4.8 | 26.0 | 24 | 21 | 18 | 2 | 15 | 14 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 4.77 |
| CL | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 94 | 25 | 0 | 1 | 1 | 2.16 | .286 | 1.16 | 5.0 | 5.4 | 13.0 | 25.0 | 14 | 6 | 6 | 0 | 15 | 36 | 0 | 20 | 2 | 0 | 0 | 1 | 0 | 2.04 |