| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 13 | 13 | 4 | 5 | 3.97 | .308 | 1.29 | 8.2 | 3.4 | 9.2 | 77.0 | 70 | 36 | 34 | 9 | 29 | 79 | 1 | 0 | 0 | 1 | 7 | 4 | 0 | 3.75 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 12 | 12 | 4 | 4 | 5.54 | .336 | 1.52 | 9.0 | 4.8 | 4.2 | 66.2 | 66 | 45 | 41 | 12 | 35 | 31 | 1 | 0 | 0 | 0 | 6 | 0 | 0 | 6.02 |
| CL | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 27 | 0 | 3 | 1 | 4.60 | .338 | 1.47 | 9.3 | 4.0 | 3.7 | 29.1 | 30 | 18 | 15 | 5 | 13 | 12 | 0 | 11 | 1 | 0 | 0 | 2 | 0 | 5.97 |
| SU | Betances, D.Betances, Dellin >> | 26 | 2014 | R | 93 | 34 | 0 | 2 | 3 | 4.50 | .254 | 1.02 | 5.5 | 3.7 | 8.0 | 44.0 | 27 | 23 | 22 | 4 | 18 | 39 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 3.64 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 27 | 0 | 2 | 0 | 2.80 | .259 | 1.05 | 5.9 | 3.6 | 8.7 | 35.1 | 23 | 12 | 11 | 4 | 14 | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.74 |