| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 91 | 19 | 19 | 7 | 9 | 3.90 | .281 | 1.16 | 7.6 | 2.8 | 9.3 | 124.2 | 105 | 55 | 54 | 23 | 39 | 128 | 1 | 0 | 0 | 1 | 12 | 2 | 1 | 4.34 |
| SP | Martinez, P.Martinez, Pedro >> | 31 | 2002 | R | 82 | 19 | 19 | 8 | 7 | 4.64 | .306 | 1.30 | 9.4 | 2.4 | 8.8 | 114.1 | 119 | 59 | 59 | 18 | 30 | 112 | 0 | 0 | 0 | 0 | 10 | 2 | 3 | 3.93 |
| SP | McKenzie, T.McKenzie, Triston >> | 24 | 2022 | R | 77 | 19 | 19 | 4 | 8 | 6.88 | .336 | 1.48 | 11.0 | 2.5 | 6.0 | 87.2 | 106 | 70 | 67 | 25 | 24 | 58 | 0 | 0 | 0 | 0 | 4 | 3 | 4 | 6.33 |
| SP | Strasburg, S.Strasburg, Stephen # >> | 28 | 2017 | R | 62 | 20 | 19 | 4 | 9 | 5.40 | .316 | 1.36 | 9.1 | 3.2 | 8.9 | 106.2 | 107 | 66 | 64 | 18 | 38 | 105 | 1 | 0 | 0 | 0 | 8 | 3 | 5 | 4.39 |
| RP | Clase, E.Clase, Emmanuel >> | 24 | 2022 | R | 94 | 55 | 0 | 0 | 1 | 3.41 | .295 | 1.25 | 9.5 | 2.0 | 8.9 | 60.2 | 63 | 23 | 23 | 5 | 13 | 59 | 0 | 5 | 1 | 0 | 0 | 0 | 2 | 2.77 |
| RP | Madson, R.Madson, Ryan >> | 37 | 2017 | R | 90 | 47 | 0 | 3 | 2 | 4.14 | .272 | 1.10 | 7.7 | 2.2 | 10.4 | 50.0 | 43 | 23 | 23 | 4 | 12 | 58 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 2.50 |
| RP | Doolittle, S.Doolittle, Sean >> | 30 | 2017 | L | 81 | 53 | 0 | 1 | 5 | 4.57 | .257 | 1.04 | 6.4 | 3.1 | 9.0 | 41.1 | 29 | 21 | 21 | 4 | 14 | 41 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 3.29 |
| RP | Albers, M.Albers, Matt >> | 34 | 2017 | R | 88 | 29 | 0 | 2 | 0 | 3.06 | .271 | 1.05 | 6.8 | 2.8 | 9.8 | 32.1 | 24 | 11 | 11 | 5 | 10 | 35 | 0 | 4 | 0 | 0 | 0 | 2 | 0 | 3.97 |
| RP | Garcia, Y.Garcia, Yimi >> | 28 | 2019 | R | 82 | 22 | 0 | 2 | 1 | 4.35 | .311 | 1.35 | 9.9 | 2.7 | 9.5 | 20.2 | 22 | 12 | 10 | 4 | 6 | 21 | 0 | 2 | 2 | 0 | 0 | 0 | 1 | 4.40 |