| SP | Leonard, D.Leonard, Dutch # >> | 22 | 1914 | L | 89 | 19 | 19 | 6 | 8 | 4.07 | .270 | 1.07 | 7.3 | 2.4 | 4.6 | 121.2 | 98 | 58 | 55 | 12 | 32 | 62 | 2 | 0 | 0 | 0 | 11 | 5 | 0 | 4.18 |
| SP | Peralta, F.Peralta, Freddy >> | 25 | 2021 | R | 85 | 18 | 18 | 10 | 4 | 3.48 | .300 | 1.24 | 6.4 | 4.8 | 9.9 | 95.2 | 68 | 42 | 37 | 12 | 51 | 105 | 0 | 0 | 0 | 0 | 5 | 4 | 1 | 4.17 |
| SP | Burnes, C.Burnes, Corbin # >> | 26 | 2021 | R | 80 | 18 | 18 | 7 | 7 | 4.29 | .290 | 1.21 | 8.2 | 2.7 | 10.6 | 113.1 | 103 | 58 | 54 | 13 | 34 | 133 | 1 | 0 | 0 | 0 | 7 | 2 | 2 | 3.10 |
| SP | Woodruff, B.Woodruff, Brandon >> | 28 | 2021 | R | 75 | 18 | 18 | 6 | 6 | 4.67 | .278 | 1.16 | 7.5 | 2.9 | 8.7 | 108.0 | 90 | 56 | 56 | 16 | 35 | 104 | 0 | 0 | 0 | 0 | 10 | 0 | 0 | 3.97 |
| RP | Richards, T.Richards, Trevor >> | 28 | 2021 | R | 78 | 40 | 0 | 2 | 0 | 3.51 | .297 | 1.19 | 6.7 | 4.1 | 8.3 | 51.1 | 38 | 22 | 20 | 8 | 23 | 47 | 0 | 5 | 1 | 0 | 0 | 4 | 3 | 4.78 |
| RP | Williams, D.Williams, Devin >> | 26 | 2021 | R | 45 | 27 | 0 | 2 | 1 | 2.50 | .265 | 1.08 | 4.5 | 5.3 | 11.5 | 36.0 | 18 | 10 | 10 | 3 | 21 | 46 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 3.28 |
| RP | Boxberger, B.Boxberger, Brad >> | 33 | 2021 | R | 56 | 22 | 0 | 1 | 3 | 4.88 | .314 | 1.38 | 9.0 | 3.4 | 8.3 | 24.0 | 24 | 13 | 13 | 4 | 9 | 22 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.46 |
| RP | Feyereisen, J.Feyereisen, J.P. >> | 28 | 2021 | R | 38 | 16 | 0 | 2 | 1 | 3.72 | .284 | 1.14 | 7.1 | 3.3 | 4.7 | 19.1 | 15 | 8 | 8 | 5 | 7 | 10 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 6.63 |
| RP | Rasmussen, D.Rasmussen, Drew # >> | 25 | 2021 | R | 43 | 20 | 0 | 2 | 2 | 4.50 | .289 | 1.19 | 6.8 | 3.9 | 5.9 | 32.0 | 24 | 18 | 16 | 4 | 14 | 21 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 4.72 |
| SP | Foster, R.Foster, Rube >> | 26 | 1914 | R | 46 | 8 | 1 | 0 | 2 | 5.86 | .376 | 1.75 | 11.3 | 4.6 | 6.4 | 35.1 | 44 | 25 | 23 | 4 | 18 | 25 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.77 |