| SP | Strasburg, S.Strasburg, Stephen >> | 34 | 2010 | R | 99 | 33 | 33 | 11 | 12 | 3.92 | .296 | 1.24 | 7.4 | 3.8 | 9.6 | 218.0 | 179 | 101 | 95 | 28 | 91 | 232 | 6 | 0 | 0 | 2 | 22 | 5 | 4 | 3.86 |
| SP | Voth, A.Voth, Austin # >> | 31 | 2019 | R | 86 | 31 | 31 | 11 | 9 | 5.02 | .315 | 1.36 | 8.6 | 3.7 | 8.8 | 161.1 | 154 | 92 | 90 | 29 | 66 | 157 | 0 | 0 | 0 | 0 | 9 | 3 | 0 | 4.68 |
| SP | Severino, L.Severino, Luis >> | 29 | 2017 | R | 95 | 30 | 30 | 13 | 10 | 5.29 | .306 | 1.27 | 9.0 | 2.5 | 8.5 | 180.1 | 179 | 112 | 106 | 35 | 50 | 170 | 4 | 0 | 0 | 1 | 14 | 10 | 7 | 4.64 |
| CL | Rainey, T.Rainey, Tanner † >> | 30 | 2020 | R | 100 | 59 | 0 | 3 | 9 | 3.39 | .291 | 1.21 | 6.8 | 4.1 | 10.6 | 61.0 | 46 | 23 | 23 | 5 | 28 | 72 | 0 | 36 | 3 | 0 | 0 | 1 | 4 | 3.13 |
| SU | Rivero, F.Rivero, Felipe >> | 31 | 2015 | L | 96 | 60 | 0 | 2 | 5 | 2.64 | .265 | 1.06 | 7.1 | 2.5 | 6.9 | 99.0 | 78 | 31 | 29 | 12 | 27 | 76 | 0 | 4 | 8 | 0 | 0 | 2 | 3 | 3.92 |
| RP | Harvey, H.Harvey, Hunter >> | 28 | 2023 | R | 76 | 72 | 0 | 5 | 3 | 3.48 | .306 | 1.30 | 8.0 | 3.7 | 9.5 | 85.1 | 76 | 34 | 33 | 8 | 35 | 90 | 0 | 2 | 2 | 0 | 0 | 2 | 1 | 3.41 |
| RP | Newberry, J.Newberry, Jake >> | 28 | 2020 | R | 84 | 54 | 0 | 3 | 2 | 5.37 | .328 | 1.45 | 7.8 | 5.2 | 10.3 | 67.0 | 58 | 41 | 40 | 8 | 39 | 77 | 0 | 2 | 4 | 0 | 0 | 1 | 2 | 4.04 |
| RP | Lorenzen, M.Lorenzen, Michael # >> | 31 | 2016 | R | 86 | 39 | 0 | 5 | 2 | 3.60 | .271 | 1.05 | 6.9 | 2.6 | 8.0 | 60.0 | 46 | 26 | 24 | 11 | 17 | 53 | 0 | 0 | 1 | 0 | 0 | 4 | 5 | 4.67 |
| RP | Wilson, S.Wilson, Steven >> | 28 | 2022 | R | 82 | 25 | 0 | 2 | 0 | 4.56 | .313 | 1.36 | 6.1 | 6.5 | 12.6 | 25.2 | 17 | 15 | 13 | 4 | 18 | 35 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 4.44 |