| SP | deGrom, J.deGrom, Jacob >> | 35 | 2021 | R | 100 | 35 | 35 | 11 | 9 | 3.72 | .272 | 1.09 | 6.9 | 2.9 | 11.0 | 205.2 | 158 | 86 | 85 | 20 | 67 | 251 | 0 | 0 | 0 | 0 | 19 | 5 | 0 | 2.87 |
| SP | Harvey, M.Harvey, Matt >> | 34 | 2012 | R | 93 | 35 | 35 | 16 | 10 | 3.95 | .297 | 1.23 | 6.9 | 4.2 | 8.0 | 232.1 | 177 | 108 | 102 | 28 | 109 | 206 | 3 | 0 | 0 | 1 | 22 | 9 | 6 | 4.32 |
| SP | Turner, J.Turner, Jacob † >> | 32 | 2012 | R | 99 | 32 | 32 | 16 | 7 | 3.61 | .278 | 1.13 | 7.2 | 3.0 | 7.4 | 204.1 | 163 | 87 | 82 | 22 | 68 | 168 | 6 | 0 | 0 | 3 | 20 | 5 | 4 | 3.83 |
| SP | Syndergaard, N.Syndergaard, Noah # >> | 30 | 2015 | R | 95 | 33 | 33 | 15 | 10 | 3.77 | .267 | 1.07 | 7.5 | 2.1 | 9.4 | 222.0 | 186 | 97 | 93 | 34 | 51 | 231 | 8 | 0 | 0 | 0 | 18 | 5 | 5 | 3.67 |
| SP | Gsellman, R.Gsellman, Robert >> | 29 | 2016 | R | 97 | 32 | 32 | 13 | 10 | 4.29 | .306 | 1.30 | 8.4 | 3.3 | 9.5 | 197.1 | 183 | 96 | 94 | 25 | 73 | 209 | 4 | 0 | 0 | 2 | 18 | 5 | 2 | 3.72 |
| RP | Familia, J.Familia, Jeurys >> | 33 | 2014 | R | 80 | 95 | 0 | 5 | 3 | 3.43 | .268 | 1.05 | 6.5 | 3.0 | 7.8 | 86.2 | 62 | 41 | 33 | 10 | 29 | 75 | 0 | 4 | 4 | 0 | 0 | 4 | 5 | 3.92 |
| RP | Mejia, J.Mejia, Jenrry # >> | 33 | 2010 | L | 73 | 91 | 0 | 4 | 1 | 4.56 | .315 | 1.36 | 6.4 | 5.9 | 5.3 | 49.1 | 35 | 26 | 25 | 9 | 32 | 29 | 0 | 7 | 5 | 0 | 0 | 1 | 2 | 6.22 |
| RP | Gilmartin, S.Gilmartin, Sean >> | 33 | 2015 | L | 72 | 57 | 0 | 4 | 2 | 2.93 | .291 | 1.19 | 5.7 | 5.3 | 7.7 | 27.2 | 17 | 9 | 9 | 4 | 16 | 23 | 0 | 4 | 2 | 0 | 0 | 1 | 1 | 5.11 |
| SP | Wheeler, Z.Wheeler, Zack >> | 33 | 2013 | R | 82 | 2 | 1 | 0 | 2 | 8.00 | .372 | 1.78 | 13.0 | 3.0 | 6.0 | 9.0 | 13 | 8 | 8 | 2 | 3 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.56 |
| RP | Smith, D.Smith, Drew # >> | 29 | 2021 | R | 77 | 33 | 0 | 1 | 3 | 6.33 | .430 | 2.19 | 10.3 | 9.3 | 12.3 | 27.0 | 31 | 19 | 19 | 3 | 28 | 37 | 0 | 4 | 0 | 0 | 0 | 2 | 0 | 5.04 |
| SP | Montero, R.Montero, Rafael >> | 32 | 2014 | R | 88 | 16 | 0 | 1 | 0 | 3.70 | .281 | 1.11 | 7.1 | 3.0 | 9.1 | 65.2 | 51 | 29 | 27 | 10 | 22 | 66 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 4.17 |
| RP | Coleman, D.Coleman, Dylan >> | 26 | 2022 | R | 67 | 24 | 0 | 0 | 0 | 6.26 | .337 | 1.52 | 9.4 | 4.3 | 10.6 | 23.0 | 24 | 16 | 16 | 6 | 11 | 27 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.48 |
| CL | Robles, H.Robles, Hansel >> | 32 | 2015 | R | 94 | 62 | 0 | 8 | 5 | 3.18 | .297 | 1.24 | 7.1 | 4.0 | 10.2 | 102.0 | 81 | 41 | 36 | 12 | 45 | 116 | 0 | 25 | 10 | 0 | 0 | 3 | 3 | 3.67 |
| RP | Sewald, P.Sewald, Paul >> | 33 | 2021 | R | 67 | 26 | 0 | 2 | 2 | 3.20 | .345 | 1.58 | 7.6 | 6.8 | 11.9 | 25.1 | 21 | 11 | 9 | 4 | 19 | 33 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 4.72 |