| SP | Wacha, M.Wacha, Michael † >> | 31 | 2013 | R | 99 | 33 | 33 | 16 | 7 | 2.90 | .263 | 1.05 | 6.5 | 3.0 | 9.7 | 202.0 | 145 | 69 | 65 | 19 | 68 | 217 | 0 | 0 | 0 | 0 | 22 | 3 | 2 | 3.13 |
| SP | Flaherty, J.Flaherty, Jack >> | 27 | 2018 | R | 96 | 32 | 32 | 13 | 12 | 3.13 | .258 | 1.02 | 6.2 | 3.0 | 10.4 | 213.0 | 147 | 79 | 74 | 22 | 70 | 247 | 5 | 0 | 0 | 3 | 19 | 5 | 4 | 3.08 |
| SP | Miller, S.Miller, Shelby # >> | 32 | 2013 | R | 83 | 32 | 32 | 9 | 21 | 5.03 | .303 | 1.30 | 9.4 | 2.3 | 9.9 | 191.1 | 200 | 109 | 107 | 37 | 48 | 211 | 5 | 0 | 0 | 1 | 12 | 2 | 3 | 4.09 |
| SP | Berrios, J.Berrios, Jose # >> | 29 | 2018 | R | 77 | 32 | 32 | 7 | 11 | 7.58 | .357 | 1.63 | 11.2 | 3.4 | 9.6 | 154.1 | 192 | 131 | 130 | 31 | 59 | 165 | 1 | 0 | 0 | 0 | 6 | 6 | 2 | 4.74 |
| RP | Helsley, R.Helsley, Ryan >> | 28 | 2022 | R | 99 | 92 | 0 | 6 | 3 | 3.58 | .278 | 1.14 | 6.7 | 3.6 | 8.8 | 110.2 | 82 | 44 | 44 | 16 | 44 | 108 | 0 | 4 | 2 | 0 | 0 | 2 | 2 | 4.18 |
| RP | Cabrera, G.Cabrera, Genesis >> | 26 | 2020 | L | 99 | 105 | 0 | 6 | 2 | 3.43 | .279 | 1.13 | 4.9 | 5.3 | 9.3 | 102.1 | 56 | 41 | 39 | 18 | 60 | 105 | 0 | 3 | 3 | 0 | 0 | 3 | 0 | 5.09 |
| RP | Siegrist, K.Siegrist, Kevin >> | 33 | 2013 | L | 97 | 84 | 0 | 2 | 2 | 2.69 | .270 | 1.09 | 5.4 | 4.5 | 9.5 | 60.1 | 36 | 20 | 18 | 9 | 30 | 63 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 4.40 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 31 | 2019 | R | 95 | 100 | 0 | 4 | 1 | 2.29 | .233 | 0.87 | 4.9 | 3.0 | 11.4 | 74.2 | 40 | 19 | 19 | 6 | 25 | 94 | 0 | 8 | 1 | 0 | 0 | 3 | 2 | 2.65 |
| RP | Tuivailala, S.Tuivailala, Sam >> | 30 | 2017 | R | 91 | 60 | 0 | 3 | 4 | 2.70 | .296 | 1.22 | 7.9 | 3.1 | 8.1 | 50.0 | 44 | 16 | 15 | 4 | 17 | 45 | 0 | 10 | 1 | 0 | 0 | 2 | 0 | 3.38 |
| RP | Rosenthal, T.Rosenthal, Trevor >> | 33 | 2013 | R | 84 | 35 | 0 | 3 | 5 | 3.31 | .269 | 1.07 | 6.8 | 3.1 | 9.3 | 32.2 | 24 | 12 | 12 | 5 | 11 | 33 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 4.09 |
| RP | Curtiss, J.Curtiss, John >> | 30 | 2020 | R | 82 | 11 | 0 | 1 | 4 | 6.97 | .392 | 1.84 | 15.3 | 1.8 | 7.2 | 10.1 | 17 | 9 | 8 | 3 | 2 | 8 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 6.20 |
| RP | Brebbia, J.Brebbia, John >> | 33 | 2017 | R | 77 | 10 | 0 | 0 | 0 | 7.20 | .318 | 1.40 | 10.8 | 1.8 | 10.8 | 10.0 | 12 | 8 | 8 | 2 | 2 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.80 |
| SP | Odorizzi, J.Odorizzi, Jake >> | 33 | 2015 | R | 68 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| RP | Romero, J.Romero, JoJo >> | 26 | 2023 | L | 64 | 70 | 0 | 1 | 1 | 2.09 | .233 | 0.88 | 5.5 | 2.4 | 10.3 | 56.0 | 34 | 14 | 13 | 4 | 15 | 64 | 0 | 8 | 4 | 0 | 0 | 2 | 0 | 2.55 |