| SP | Glasnow, T.Glasnow, Tyler >> | 29 | 2021 | R | 97 | 35 | 35 | 13 | 13 | 2.97 | .262 | 1.04 | 5.9 | 3.4 | 9.8 | 239.1 | 158 | 80 | 79 | 25 | 91 | 260 | 6 | 0 | 0 | 2 | 25 | 6 | 12 | 3.40 |
| SP | McClanahan, S.McClanahan, Shane # >> | 26 | 2022 | L | 90 | 35 | 35 | 11 | 14 | 4.76 | .303 | 1.27 | 8.2 | 3.3 | 9.8 | 196.2 | 178 | 104 | 104 | 32 | 72 | 213 | 0 | 0 | 0 | 0 | 15 | 6 | 6 | 4.14 |
| SP | Cabrera, E.Cabrera, Edward >> | 25 | 2022 | R | 90 | 34 | 34 | 12 | 7 | 4.10 | .317 | 1.36 | 7.0 | 5.2 | 9.6 | 167.0 | 130 | 77 | 76 | 20 | 97 | 178 | 0 | 0 | 0 | 0 | 13 | 5 | 6 | 4.26 |
| SP | Chirinos, Y.Chirinos, Yonny # >> | 29 | 2019 | R | 84 | 33 | 33 | 13 | 7 | 4.47 | .282 | 1.16 | 8.4 | 2.1 | 8.2 | 179.0 | 167 | 90 | 89 | 30 | 41 | 163 | 0 | 0 | 0 | 0 | 17 | 3 | 4 | 4.09 |
| SP | Marquez, G.Marquez, German >> | 28 | 2018 | R | 81 | 32 | 32 | 12 | 9 | 5.51 | .324 | 1.38 | 9.5 | 2.9 | 11.2 | 181.1 | 191 | 115 | 111 | 37 | 59 | 225 | 4 | 0 | 0 | 1 | 12 | 11 | 3 | 4.33 |
| RP | Ramos, E.Ramos, Edubray >> | 30 | 2016 | R | 92 | 62 | 0 | 8 | 5 | 3.95 | .296 | 1.25 | 8.4 | 2.9 | 9.7 | 93.1 | 87 | 41 | 41 | 16 | 30 | 100 | 0 | 14 | 1 | 0 | 0 | 1 | 0 | 4.09 |
| RP | Morgan, E.Morgan, Eli # >> | 27 | 2022 | R | 88 | 28 | 0 | 2 | 4 | 5.17 | .304 | 1.28 | 9.6 | 2.0 | 8.1 | 31.1 | 33 | 19 | 18 | 4 | 7 | 28 | 0 | 5 | 3 | 0 | 0 | 1 | 0 | 3.65 |
| RP | Kopech, M.Kopech, Michael >> | 27 | 2021 | R | 88 | 16 | 0 | 2 | 1 | 6.19 | .324 | 1.38 | 9.0 | 3.4 | 9.6 | 16.0 | 16 | 11 | 11 | 3 | 6 | 17 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.63 |
| RP | Bednar, D.Bednar, David >> | 28 | 2021 | R | 87 | 13 | 0 | 1 | 0 | 1.54 | .286 | 1.11 | 5.7 | 4.9 | 11.5 | 11.2 | 7 | 2 | 2 | 2 | 6 | 14 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.73 |
| RP | Santillan, T.Santillan, Tony >> | 26 | 2021 | R | 83 | 18 | 0 | 1 | 0 | 4.15 | .337 | 1.52 | 7.7 | 6.4 | 12.0 | 21.2 | 18 | 10 | 10 | 3 | 15 | 28 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.33 |
| SP | Alcantara, S.Alcantara, Sandy >> | 27 | 2022 | R | 80 | 32 | 0 | 9 | 5 | 3.65 | .306 | 1.32 | 8.6 | 3.3 | 7.4 | 160.1 | 152 | 69 | 65 | 23 | 59 | 132 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.34 |