| SP | Norris, D.Norris, Daniel >> | 30 | 2015 | L | 94 | 33 | 33 | 11 | 16 | 5.30 | .306 | 1.31 | 8.6 | 3.2 | 7.5 | 181.2 | 173 | 117 | 107 | 41 | 65 | 150 | 1 | 0 | 0 | 0 | 16 | 2 | 3 | 5.40 |
| SP | Fulmer, M.Fulmer, Michael # >> | 30 | 2016 | R | 87 | 27 | 27 | 8 | 14 | 4.83 | .293 | 1.23 | 9.1 | 1.9 | 7.9 | 190.0 | 192 | 103 | 102 | 39 | 41 | 167 | 5 | 0 | 0 | 1 | 10 | 3 | 5 | 4.61 |
| SP | Scherzer, M.Scherzer, Max # >> | 39 | 2021 | R | 85 | 30 | 30 | 8 | 14 | 5.50 | .335 | 1.48 | 10.1 | 3.3 | 10.3 | 160.1 | 179 | 106 | 98 | 20 | 58 | 183 | 0 | 0 | 0 | 0 | 14 | 5 | 1 | 3.52 |
| CL | Rondon, B.Rondon, Bruce † >> | 32 | 2016 | R | 98 | 57 | 0 | 8 | 5 | 2.38 | .247 | 0.97 | 5.6 | 3.1 | 11.1 | 72.0 | 45 | 19 | 19 | 4 | 25 | 89 | 0 | 26 | 2 | 0 | 0 | 1 | 1 | 2.33 |
| SU | Garcia, J.Garcia, Jarlin >> | 30 | 2017 | L | 81 | 86 | 0 | 2 | 2 | 3.68 | .286 | 1.19 | 8.2 | 2.5 | 7.4 | 93.0 | 85 | 41 | 38 | 15 | 26 | 76 | 0 | 3 | 3 | 0 | 0 | 1 | 1 | 4.33 |
| RP | Alburquerque, A.Alburquerque, Al >> | 37 | 2011 | R | 80 | 88 | 0 | 1 | 1 | 2.24 | .265 | 1.06 | 5.6 | 3.9 | 11.3 | 80.1 | 50 | 23 | 20 | 4 | 35 | 100 | 0 | 0 | 1 | 0 | 0 | 2 | 2 | 2.54 |
| RP | Okert, S.Okert, Steven >> | 31 | 2021 | L | 78 | 68 | 0 | 3 | 2 | 2.97 | .297 | 1.25 | 7.1 | 4.3 | 11.5 | 57.2 | 45 | 23 | 19 | 5 | 27 | 73 | 0 | 3 | 3 | 0 | 0 | 1 | 2 | 3.05 |
| RP | Neris, H.Neris, Hector >> | 34 | 2023 | R | 76 | 77 | 0 | 1 | 1 | 4.48 | .335 | 1.46 | 7.5 | 5.7 | 11.3 | 62.1 | 52 | 32 | 31 | 6 | 39 | 78 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 3.77 |
| RP | Tepera, R.Tepera, Ryan # >> | 35 | 2021 | R | 75 | 59 | 0 | 1 | 2 | 5.21 | .326 | 1.39 | 8.4 | 4.1 | 11.8 | 48.1 | 45 | 31 | 28 | 12 | 22 | 63 | 0 | 0 | 0 | 0 | 0 | 3 | 7 | 5.19 |
| SP | Darvish, Y.Darvish, Yu >> | 36 | 2022 | R | 75 | 6 | 6 | 4 | 1 | 5.00 | .285 | 1.17 | 8.0 | 2.5 | 10.5 | 36.0 | 32 | 20 | 20 | 7 | 10 | 42 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 4.11 |
| SP | Skubal, T.Skubal, Tarik >> | 26 | 2021 | L | 58 | 6 | 6 | 2 | 3 | 4.50 | .342 | 1.56 | 10.7 | 3.4 | 9.3 | 32.0 | 38 | 16 | 16 | 9 | 12 | 33 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 5.72 |
| RP | Holton, T.Holton, Tyler # >> | 27 | 2023 | L | 81 | 80 | 0 | 0 | 2 | 3.74 | .315 | 1.34 | 8.4 | 3.8 | 8.6 | 74.2 | 69 | 34 | 31 | 8 | 31 | 71 | 0 | 1 | 0 | 0 | 0 | 3 | 2 | 3.86 |
| SP | Eovaldi, N.Eovaldi, Nathan >> | 33 | 2013 | R | 74 | 8 | 3 | 2 | 3 | 7.71 | .370 | 1.71 | 12.0 | 3.4 | 8.6 | 21.0 | 28 | 18 | 18 | 1 | 8 | 20 | 0 | 1 | 0 | 0 | 1 | 1 | 0 | 3.00 |