| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 97 | 34 | 34 | 9 | 14 | 4.32 | .312 | 1.31 | 7.6 | 4.2 | 10.0 | 223.0 | 189 | 110 | 107 | 31 | 103 | 247 | 1 | 0 | 0 | 1 | 20 | 12 | 3 | 4.14 |
| SP | Valenzuela, F.Valenzuela, Fernando # >> | 21 | 1981 | L | 60 | 32 | 32 | 7 | 18 | 4.77 | .331 | 1.46 | 9.8 | 3.4 | 8.3 | 218.2 | 238 | 126 | 116 | 29 | 82 | 200 | 4 | 0 | 0 | 1 | 15 | 5 | 4 | 4.09 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 57 | 32 | 32 | 9 | 15 | 5.72 | .365 | 1.68 | 11.2 | 4.0 | 9.1 | 204.2 | 253 | 141 | 130 | 28 | 91 | 206 | 1 | 0 | 0 | 0 | 16 | 9 | 10 | 4.24 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 94 | 0 | 6 | 8 | 4.44 | .310 | 1.32 | 7.8 | 4.1 | 9.9 | 129.2 | 112 | 64 | 64 | 19 | 59 | 142 | 0 | 5 | 7 | 0 | 0 | 4 | 3 | 4.18 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 79 | 0 | 6 | 4 | 3.36 | .298 | 1.25 | 6.8 | 4.5 | 10.0 | 93.2 | 70 | 36 | 35 | 11 | 47 | 103 | 0 | 8 | 2 | 0 | 0 | 2 | 6 | 3.90 |
| RP | Pressly, R.Pressly, Ryan >> | 30 | 2019 | R | 53 | 40 | 0 | 5 | 2 | 3.92 | .291 | 1.21 | 8.1 | 2.9 | 11.2 | 41.1 | 37 | 18 | 18 | 8 | 13 | 51 | 0 | 5 | 1 | 0 | 0 | 1 | 4 | 4.07 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 46 | 37 | 0 | 2 | 1 | 4.70 | .321 | 1.38 | 9.0 | 3.5 | 9.5 | 59.1 | 59 | 31 | 31 | 7 | 23 | 62 | 0 | 0 | 1 | 0 | 0 | 2 | 3 | 3.71 |