| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 28 | 28 | 12 | 8 | 3.42 | .269 | 1.09 | 7.2 | 2.6 | 10.3 | 200.0 | 159 | 83 | 76 | 23 | 58 | 228 | 3 | 0 | 0 | 0 | 18 | 4 | 2 | 3.15 |
| SP | Snell, B.Snell, Blake # >> | 25 | 2018 | L | 88 | 27 | 27 | 14 | 8 | 3.58 | .277 | 1.14 | 7.5 | 2.7 | 9.3 | 178.1 | 149 | 71 | 71 | 21 | 54 | 184 | 0 | 0 | 0 | 0 | 17 | 2 | 9 | 3.41 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 70 | 26 | 26 | 9 | 11 | 4.86 | .314 | 1.35 | 8.2 | 4.1 | 7.5 | 164.2 | 149 | 93 | 89 | 26 | 74 | 136 | 1 | 0 | 0 | 1 | 8 | 3 | 1 | 4.81 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 68 | 24 | 24 | 10 | 6 | 3.75 | .309 | 1.34 | 7.6 | 4.5 | 9.2 | 151.0 | 127 | 65 | 63 | 14 | 75 | 154 | 0 | 0 | 0 | 0 | 14 | 1 | 3 | 3.68 |
| SP | Hamels, C.Hamels, Cole # >> | 28 | 2011 | L | 62 | 25 | 25 | 6 | 11 | 5.46 | .322 | 1.41 | 10.4 | 2.3 | 7.3 | 148.1 | 171 | 92 | 90 | 33 | 38 | 120 | 0 | 0 | 0 | 0 | 12 | 2 | 3 | 5.09 |
| RP | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 73 | 0 | 10 | 3 | 3.12 | .268 | 1.08 | 7.3 | 2.4 | 9.0 | 101.0 | 82 | 36 | 35 | 18 | 27 | 101 | 0 | 10 | 2 | 0 | 0 | 2 | 1 | 4.18 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 68 | 0 | 2 | 7 | 3.71 | .294 | 1.21 | 7.9 | 3.0 | 8.5 | 85.0 | 75 | 36 | 35 | 9 | 28 | 80 | 0 | 11 | 4 | 0 | 0 | 3 | 3 | 3.59 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 67 | 50 | 0 | 1 | 3 | 3.12 | .282 | 1.18 | 6.8 | 3.9 | 6.8 | 57.2 | 43 | 23 | 20 | 12 | 25 | 43 | 0 | 5 | 5 | 0 | 0 | 0 | 0 | 5.54 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 59 | 41 | 0 | 2 | 2 | 4.17 | .357 | 1.66 | 8.3 | 7.0 | 11.8 | 36.2 | 33 | 22 | 17 | 2 | 28 | 47 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 3.44 |
| RP | Pressly, R.Pressly, Ryan >> | 30 | 2019 | R | 53 | 29 | 0 | 0 | 3 | 5.88 | .313 | 1.37 | 9.8 | 2.7 | 10.1 | 33.2 | 36 | 22 | 22 | 9 | 10 | 37 | 0 | 3 | 2 | 0 | 0 | 0 | 2 | 5.21 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 55 | 2 | 2 | 0 | 1 | 1.35 | .286 | 1.20 | 8.3 | 2.8 | 9.0 | 13.1 | 12 | 3 | 2 | 1 | 4 | 13 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 2.92 |