| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 29 | 29 | 14 | 7 | 2.74 | .258 | 1.00 | 6.3 | 2.7 | 7.8 | 213.2 | 150 | 70 | 65 | 18 | 64 | 185 | 13 | 0 | 0 | 3 | 20 | 9 | 7 | 3.39 |
| SP | Fernandez, S.Fernandez, Sid $ >> | 23 | 1985 | L | 49 | 28 | 28 | 11 | 9 | 3.64 | .312 | 1.35 | 7.5 | 4.7 | 7.0 | 178.0 | 148 | 74 | 72 | 18 | 92 | 138 | 0 | 0 | 0 | 0 | 18 | 2 | 1 | 4.35 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 92 | 28 | 28 | 11 | 7 | 3.72 | .313 | 1.35 | 9.0 | 3.2 | 7.1 | 183.2 | 182 | 79 | 76 | 14 | 66 | 144 | 4 | 0 | 0 | 0 | 18 | 3 | 5 | 3.55 |
| SP | Mathewson, C.Mathewson, Christy † >> | 28 | 1908 | R | 83 | 27 | 27 | 18 | 5 | 3.09 | .243 | 0.96 | 6.9 | 1.7 | 4.5 | 192.0 | 148 | 67 | 66 | 19 | 36 | 96 | 8 | 0 | 0 | 3 | 17 | 1 | 2 | 3.86 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 63 | 0 | 1 | 8 | 3.23 | .273 | 1.13 | 6.6 | 3.5 | 8.7 | 64.0 | 47 | 24 | 23 | 4 | 25 | 62 | 0 | 36 | 5 | 0 | 0 | 0 | 5 | 3.05 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 93 | 73 | 0 | 6 | 6 | 5.00 | .280 | 1.17 | 8.0 | 2.6 | 9.5 | 84.2 | 75 | 48 | 47 | 18 | 24 | 89 | 0 | 1 | 6 | 0 | 0 | 0 | 0 | 4.52 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 56 | 0 | 5 | 3 | 2.91 | .253 | 1.01 | 5.8 | 3.3 | 6.8 | 68.0 | 44 | 22 | 22 | 8 | 25 | 51 | 0 | 1 | 3 | 0 | 0 | 0 | 1 | 4.13 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 85 | 31 | 0 | 5 | 1 | 5.63 | .294 | 1.22 | 8.7 | 2.3 | 10.7 | 32.0 | 31 | 20 | 20 | 8 | 8 | 38 | 0 | 1 | 2 | 0 | 0 | 1 | 2 | 4.72 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 24 | 0 | 2 | 0 | 1.60 | .273 | 1.10 | 6.3 | 3.8 | 6.8 | 33.2 | 23 | 6 | 6 | 2 | 14 | 25 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.64 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 26 | 0 | 1 | 1 | 5.73 | .400 | 2.00 | 11.5 | 6.5 | 8.6 | 22.0 | 28 | 17 | 14 | 3 | 16 | 21 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 5.05 |