| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 18 | 18 | 5 | 9 | 4.58 | .303 | 1.27 | 9.3 | 2.1 | 9.1 | 118.0 | 122 | 65 | 60 | 18 | 28 | 119 | 1 | 0 | 0 | 0 | 11 | 4 | 1 | 3.78 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 16 | 16 | 7 | 6 | 4.74 | .315 | 1.37 | 9.3 | 3.0 | 8.5 | 104.1 | 108 | 56 | 55 | 16 | 35 | 98 | 0 | 0 | 0 | 0 | 8 | 1 | 2 | 4.15 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 17 | 17 | 6 | 8 | 5.72 | .339 | 1.52 | 9.8 | 4.0 | 5.2 | 100.2 | 109 | 73 | 64 | 18 | 44 | 58 | 2 | 0 | 0 | 1 | 6 | 2 | 2 | 5.56 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 17 | 17 | 5 | 4 | 5.10 | .324 | 1.42 | 9.7 | 3.2 | 7.8 | 107.2 | 115 | 66 | 61 | 14 | 38 | 93 | 0 | 0 | 0 | 0 | 6 | 2 | 2 | 4.08 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 40 | 0 | 3 | 0 | 1.57 | .233 | 0.91 | 6.7 | 1.6 | 8.6 | 46.0 | 34 | 8 | 8 | 2 | 8 | 44 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.17 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 29 | 0 | 3 | 2 | 2.36 | .266 | 1.09 | 7.3 | 2.8 | 10.7 | 26.2 | 21 | 9 | 7 | 4 | 8 | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.54 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 15 | 0 | 1 | 1 | 2.13 | .377 | 1.82 | 6.0 | 11.3 | 10.5 | 12.2 | 8 | 3 | 3 | 0 | 15 | 14 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.42 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 7 | 0 | 0 | 1 | 1.93 | .263 | 1.07 | 3.0 | 7.0 | 5.0 | 9.1 | 3 | 3 | 2 | 1 | 7 | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 5.67 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 9 | 0 | 0 | 0 | 1.42 | .191 | 0.71 | 4.5 | 2.3 | 2.3 | 12.2 | 6 | 2 | 2 | 2 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.42 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 33 | 0 | 5 | 4 | 2.00 | .245 | 0.92 | 5.8 | 2.5 | 7.0 | 36.0 | 23 | 12 | 8 | 2 | 10 | 28 | 0 | 18 | 3 | 0 | 0 | 2 | 0 | 3.17 |
| RP | Rhodes, A.Rhodes, Arthur >> | 32 | 2001 | L | 64 | 48 | 0 | 0 | 1 | 4.28 | .279 | 1.13 | 7.9 | 2.5 | 9.8 | 33.2 | 29 | 16 | 16 | 5 | 9 | 36 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.70 |