| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 18 | 18 | 6 | 8 | 3.67 | .280 | 1.16 | 7.1 | 3.4 | 9.6 | 125.0 | 98 | 59 | 51 | 13 | 47 | 133 | 1 | 0 | 0 | 0 | 10 | 1 | 3 | 3.38 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 17 | 17 | 6 | 6 | 3.88 | .301 | 1.26 | 8.0 | 3.3 | 4.5 | 123.0 | 110 | 59 | 53 | 12 | 45 | 62 | 3 | 0 | 0 | 1 | 11 | 4 | 1 | 4.46 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 67 | 16 | 16 | 3 | 9 | 8.29 | .367 | 1.71 | 12.2 | 3.2 | 7.6 | 97.2 | 132 | 92 | 90 | 24 | 35 | 82 | 1 | 0 | 0 | 0 | 1 | 3 | 8 | 5.70 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 46 | 0 | 2 | 0 | 1.92 | .256 | 1.00 | 5.8 | 3.2 | 8.1 | 61.0 | 39 | 14 | 13 | 6 | 22 | 55 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 3.66 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 33 | 0 | 1 | 3 | 4.54 | .323 | 1.38 | 9.0 | 3.6 | 10.9 | 37.2 | 37 | 22 | 19 | 2 | 15 | 45 | 0 | 6 | 1 | 0 | 0 | 2 | 2 | 2.65 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 24 | 0 | 3 | 2 | 5.22 | .353 | 1.64 | 9.0 | 5.9 | 11.2 | 29.1 | 29 | 17 | 17 | 7 | 19 | 36 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 5.62 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 21 | 0 | 2 | 1 | 3.52 | .324 | 1.43 | 7.4 | 5.5 | 7.4 | 23.0 | 19 | 9 | 9 | 0 | 14 | 19 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 3.17 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 9 | 0 | 2 | 0 | 6.94 | .314 | 1.37 | 9.0 | 4.1 | 6.5 | 11.2 | 11 | 9 | 9 | 2 | 5 | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 5.27 |