| SP | deGrom, J.deGrom, Jacob † >> | 33 | 2021 | R | 100 | 18 | 18 | 10 | 3 | 2.77 | .257 | 1.02 | 6.7 | 2.6 | 8.3 | 123.2 | 91 | 41 | 38 | 14 | 35 | 114 | 1 | 0 | 0 | 1 | 14 | 2 | 0 | 3.53 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 17 | 17 | 8 | 7 | 6.05 | .319 | 1.38 | 9.9 | 2.5 | 6.8 | 96.2 | 106 | 65 | 65 | 26 | 27 | 73 | 0 | 0 | 0 | 0 | 6 | 3 | 2 | 5.94 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 77 | 17 | 17 | 9 | 8 | 3.76 | .253 | 1.00 | 7.3 | 1.7 | 6.0 | 127.0 | 103 | 55 | 53 | 18 | 24 | 85 | 9 | 0 | 0 | 3 | 8 | 2 | 0 | 4.12 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 36 | 0 | 3 | 0 | 3.21 | .302 | 1.26 | 5.9 | 5.6 | 10.9 | 47.2 | 31 | 18 | 17 | 4 | 29 | 57 | 0 | 3 | 0 | 0 | 0 | 2 | 3 | 3.66 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 94 | 33 | 0 | 1 | 2 | 4.73 | .322 | 1.38 | 7.9 | 4.5 | 7.9 | 40.0 | 35 | 21 | 21 | 5 | 20 | 35 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 4.53 |
| RP | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 92 | 27 | 0 | 1 | 0 | 2.43 | .315 | 1.32 | 8.5 | 3.5 | 9.8 | 33.1 | 31 | 9 | 9 | 3 | 13 | 36 | 0 | 5 | 1 | 0 | 0 | 2 | 0 | 3.36 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 89 | 18 | 0 | 0 | 1 | 3.75 | .308 | 1.29 | 7.5 | 4.1 | 7.5 | 24.0 | 20 | 10 | 10 | 2 | 11 | 20 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.92 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 85 | 15 | 0 | 1 | 0 | 4.60 | .338 | 1.53 | 11.4 | 3.0 | 12.0 | 15.2 | 19 | 11 | 8 | 4 | 5 | 20 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 4.80 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 15 | 0 | 0 | 1 | 2.86 | .283 | 1.14 | 7.8 | 2.5 | 10.2 | 22.0 | 19 | 7 | 7 | 2 | 6 | 25 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.86 |
| SP | Nichols, K.Nichols, Kid >> | 35 | 1904 | R | 23 | 2 | 0 | 0 | 1 | 3.86 | .364 | 1.71 | 18.0 | 0.0 | 4.5 | 2.1 | 4 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.00 |