| SP | Verlander, J.Verlander, Justin $ >> | 36 | 2019 | R | 99 | 29 | 29 | 10 | 11 | 3.99 | .312 | 1.34 | 9.0 | 3.1 | 7.4 | 196.0 | 195 | 89 | 87 | 23 | 67 | 161 | 0 | 0 | 0 | 0 | 15 | 5 | 4 | 3.98 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 28 | 28 | 6 | 13 | 5.10 | .317 | 1.37 | 9.4 | 3.0 | 7.8 | 189.0 | 197 | 115 | 107 | 28 | 62 | 164 | 0 | 0 | 0 | 0 | 12 | 4 | 3 | 4.24 |
| SP | Clemens, R.Clemens, Roger $$ >> | 24 | 1986 | R | 69 | 28 | 28 | 9 | 16 | 4.60 | .299 | 1.26 | 7.7 | 3.7 | 5.3 | 201.1 | 172 | 111 | 103 | 31 | 82 | 118 | 8 | 0 | 0 | 1 | 16 | 4 | 8 | 5.11 |
| CL | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 95 | 50 | 0 | 3 | 7 | 2.95 | .270 | 1.07 | 5.1 | 4.6 | 8.7 | 55.0 | 31 | 19 | 18 | 5 | 28 | 53 | 0 | 30 | 2 | 0 | 0 | 2 | 0 | 3.89 |
| SU | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 52 | 0 | 4 | 2 | 2.97 | .248 | 0.97 | 7.7 | 1.1 | 9.5 | 57.2 | 49 | 20 | 19 | 4 | 7 | 60 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 2.23 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 72 | 0 | 1 | 2 | 2.58 | .283 | 1.18 | 6.6 | 4.2 | 9.0 | 52.1 | 38 | 20 | 15 | 9 | 24 | 52 | 0 | 1 | 3 | 0 | 0 | 0 | 8 | 4.63 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 45 | 0 | 3 | 2 | 2.63 | .273 | 1.13 | 6.8 | 3.4 | 7.5 | 48.0 | 36 | 21 | 14 | 4 | 18 | 40 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 3.54 |