| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 25 | 25 | 14 | 7 | 3.39 | .277 | 1.11 | 7.0 | 3.0 | 8.0 | 169.2 | 131 | 70 | 64 | 21 | 57 | 151 | 2 | 0 | 0 | 1 | 17 | 7 | 1 | 3.96 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 82 | 24 | 24 | 12 | 5 | 3.97 | .292 | 1.20 | 9.0 | 1.8 | 4.0 | 158.2 | 158 | 73 | 70 | 20 | 32 | 70 | 5 | 0 | 0 | 3 | 12 | 6 | 2 | 4.48 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 84 | 24 | 24 | 11 | 3 | 3.69 | .269 | 1.09 | 7.8 | 2.1 | 8.3 | 168.1 | 145 | 72 | 69 | 20 | 39 | 154 | 5 | 0 | 0 | 1 | 17 | 2 | 3 | 3.45 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 23 | 23 | 6 | 9 | 4.83 | .323 | 1.42 | 8.7 | 4.1 | 7.8 | 136.0 | 131 | 79 | 73 | 14 | 62 | 118 | 0 | 0 | 0 | 0 | 8 | 2 | 0 | 4.01 |
| RP | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 62 | 0 | 7 | 1 | 2.38 | .261 | 1.04 | 6.6 | 2.8 | 9.1 | 64.1 | 47 | 19 | 17 | 8 | 20 | 65 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 3.58 |
| RP | Miller, A.Miller, Andrew >> | 31 | 2016 | L | 91 | 56 | 0 | 4 | 1 | 2.43 | .230 | 0.88 | 6.4 | 1.6 | 7.9 | 55.2 | 39 | 16 | 15 | 5 | 10 | 48 | 0 | 6 | 2 | 0 | 0 | 1 | 2 | 3.04 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 89 | 68 | 0 | 2 | 1 | 2.19 | .256 | 1.03 | 6.8 | 2.5 | 8.0 | 53.1 | 40 | 13 | 13 | 3 | 15 | 47 | 0 | 8 | 2 | 0 | 0 | 0 | 3 | 2.81 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 48 | 0 | 5 | 2 | 1.90 | .220 | 0.82 | 4.5 | 3.0 | 8.4 | 42.2 | 21 | 9 | 9 | 3 | 14 | 39 | 0 | 5 | 0 | 0 | 0 | 1 | 0 | 3.14 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 50 | 0 | 0 | 6 | 3.05 | .222 | 0.83 | 5.5 | 2.0 | 8.6 | 44.1 | 27 | 15 | 15 | 3 | 10 | 42 | 0 | 5 | 1 | 0 | 0 | 1 | 6 | 2.73 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 71 | 27 | 0 | 3 | 3 | 3.60 | .266 | 1.06 | 6.9 | 2.6 | 6.9 | 35.0 | 27 | 15 | 14 | 7 | 10 | 27 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 5.00 |