| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 34 | 34 | 14 | 7 | 3.29 | .269 | 1.09 | 7.2 | 2.7 | 8.7 | 227.1 | 181 | 86 | 83 | 21 | 67 | 220 | 5 | 0 | 0 | 2 | 23 | 3 | 5 | 3.19 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 33 | 33 | 9 | 10 | 4.40 | .311 | 1.34 | 8.8 | 3.3 | 4.4 | 204.1 | 199 | 106 | 100 | 18 | 74 | 100 | 2 | 0 | 0 | 0 | 18 | 4 | 6 | 4.31 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 32 | 32 | 13 | 14 | 5.60 | .333 | 1.47 | 10.3 | 3.0 | 7.2 | 180.0 | 205 | 114 | 112 | 28 | 59 | 144 | 1 | 0 | 0 | 0 | 15 | 6 | 3 | 4.51 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 32 | 32 | 9 | 12 | 5.31 | .329 | 1.47 | 9.6 | 3.6 | 4.0 | 186.1 | 199 | 118 | 110 | 23 | 74 | 83 | 2 | 0 | 0 | 0 | 13 | 1 | 2 | 4.92 |
| SP | Hubbell, C.Hubbell, Carl >> | 30 | 1933 | L | 37 | 32 | 31 | 9 | 13 | 4.65 | .315 | 1.36 | 10.1 | 2.1 | 4.3 | 182.0 | 204 | 95 | 94 | 19 | 43 | 86 | 1 | 1 | 0 | 0 | 17 | 4 | 1 | 4.19 |
| RP | Betances, D.Betances, Dellin >> | 26 | 2014 | R | 94 | 100 | 0 | 6 | 6 | 4.93 | .315 | 1.37 | 8.1 | 4.3 | 9.5 | 118.2 | 106 | 69 | 65 | 9 | 57 | 124 | 0 | 2 | 4 | 0 | 0 | 1 | 1 | 3.36 |
| CL | Nathan, J.Nathan, Joe † >> | 32 | 2006 | R | 86 | 83 | 0 | 4 | 14 | 4.34 | .297 | 1.25 | 7.9 | 3.4 | 6.9 | 101.2 | 89 | 54 | 49 | 12 | 38 | 77 | 0 | 33 | 4 | 0 | 0 | 2 | 2 | 4.21 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 68 | 0 | 0 | 2 | 4.05 | .305 | 1.32 | 6.9 | 4.9 | 8.4 | 91.0 | 70 | 42 | 41 | 7 | 50 | 85 | 0 | 2 | 2 | 0 | 0 | 0 | 1 | 3.78 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 67 | 0 | 5 | 3 | 3.78 | .324 | 1.43 | 7.4 | 5.5 | 8.0 | 83.1 | 68 | 36 | 35 | 9 | 51 | 74 | 0 | 2 | 2 | 0 | 0 | 1 | 6 | 4.51 |