| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 99 | 33 | 33 | 26 | 3 | 2.39 | .233 | 0.90 | 7.0 | 1.1 | 9.0 | 267.2 | 209 | 72 | 71 | 34 | 33 | 266 | 12 | 0 | 0 | 2 | 26 | 2 | 3 | 3.06 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 34 | 34 | 12 | 12 | 3.50 | .283 | 1.16 | 7.1 | 3.3 | 5.5 | 213.2 | 168 | 89 | 83 | 17 | 79 | 131 | 0 | 0 | 0 | 0 | 22 | 6 | 2 | 4.00 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 33 | 33 | 20 | 9 | 4.04 | .302 | 1.29 | 8.8 | 2.8 | 5.1 | 229.1 | 224 | 107 | 103 | 22 | 72 | 129 | 6 | 0 | 0 | 2 | 17 | 1 | 7 | 4.08 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 67 | 0 | 0 | 2 | 2.78 | .245 | 0.96 | 5.8 | 3.0 | 10.0 | 64.2 | 41 | 21 | 20 | 6 | 21 | 71 | 0 | 54 | 5 | 0 | 0 | 1 | 1 | 3.03 |
| SU | Betances, D.Betances, Dellin >> | 26 | 2014 | R | 94 | 63 | 0 | 4 | 1 | 2.74 | .276 | 1.13 | 6.0 | 4.3 | 9.7 | 65.2 | 43 | 22 | 20 | 6 | 31 | 70 | 0 | 1 | 5 | 0 | 0 | 1 | 3 | 3.52 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 34 | 0 | 1 | 2 | 3.81 | .280 | 1.16 | 7.7 | 2.9 | 8.7 | 28.1 | 24 | 12 | 12 | 3 | 9 | 27 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.43 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 4 | 0 | 0 | 1 | 3.38 | .111 | 0.38 | 4.5 | 0.0 | 13.5 | 2.2 | 1 | 1 | 1 | 1 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.50 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 33 | 33 | 13 | 12 | 4.44 | .311 | 1.33 | 8.5 | 3.5 | 5.4 | 212.2 | 200 | 109 | 105 | 30 | 82 | 127 | 5 | 0 | 0 | 2 | 18 | 6 | 2 | 4.89 |