| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 34 | 34 | 11 | 15 | 4.27 | .302 | 1.29 | 8.1 | 3.5 | 7.8 | 219.1 | 197 | 107 | 104 | 29 | 85 | 191 | 2 | 0 | 0 | 0 | 19 | 3 | 4 | 4.18 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 32 | 32 | 6 | 15 | 4.63 | .318 | 1.38 | 9.2 | 3.3 | 5.8 | 225.2 | 229 | 122 | 116 | 27 | 83 | 144 | 2 | 0 | 0 | 0 | 16 | 4 | 5 | 4.44 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 60 | 33 | 33 | 16 | 17 | 3.91 | .292 | 1.23 | 8.6 | 2.5 | 4.9 | 248.1 | 238 | 110 | 108 | 22 | 68 | 134 | 14 | 0 | 0 | 3 | 17 | 2 | 3 | 3.92 |
| SP | Saberhagen, B.Saberhagen, Bret # >> | 25 | 1989 | R | 51 | 32 | 32 | 12 | 14 | 4.56 | .312 | 1.34 | 9.8 | 2.3 | 5.7 | 215.1 | 234 | 113 | 109 | 28 | 55 | 137 | 6 | 0 | 0 | 3 | 16 | 4 | 7 | 4.24 |
| SP | Cuellar, M.Cuellar, Mike >> | 32 | 1969 | L | 44 | 31 | 31 | 10 | 12 | 4.95 | .333 | 1.48 | 9.1 | 4.2 | 4.2 | 209.0 | 211 | 122 | 115 | 21 | 98 | 98 | 2 | 0 | 0 | 0 | 13 | 4 | 4 | 4.83 |
| RP | Benoit, J.Benoit, Joaquin † >> | 33 | 2010 | R | 95 | 87 | 0 | 7 | 4 | 3.93 | .311 | 1.34 | 8.8 | 3.3 | 8.3 | 110.0 | 107 | 54 | 48 | 14 | 40 | 101 | 0 | 10 | 2 | 0 | 0 | 2 | 2 | 3.96 |
| RP | Soria, J.Soria, Joakim # >> | 24 | 2008 | R | 67 | 72 | 0 | 3 | 5 | 5.54 | .313 | 1.35 | 8.7 | 3.5 | 6.8 | 87.2 | 84 | 58 | 54 | 19 | 34 | 66 | 0 | 8 | 1 | 0 | 0 | 2 | 0 | 5.56 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 49 | 0 | 3 | 1 | 3.27 | .293 | 1.22 | 9.0 | 2.1 | 8.7 | 52.1 | 52 | 21 | 19 | 7 | 12 | 50 | 0 | 7 | 0 | 0 | 0 | 1 | 1 | 3.58 |