| SP | Scherzer, M.Scherzer, Max † # >> | 33 | 2017 | R | 95 | 18 | 18 | 11 | 4 | 2.79 | .261 | 1.04 | 7.1 | 2.2 | 6.6 | 129.0 | 102 | 41 | 40 | 11 | 32 | 95 | 2 | 0 | 0 | 1 | 13 | 3 | 1 | 3.45 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 17 | 17 | 4 | 10 | 6.24 | .344 | 1.53 | 9.9 | 3.9 | 4.0 | 106.2 | 117 | 82 | 74 | 16 | 46 | 47 | 1 | 0 | 0 | 0 | 5 | 5 | 4 | 5.52 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 17 | 17 | 6 | 7 | 5.53 | .358 | 1.62 | 10.1 | 4.5 | 4.9 | 94.1 | 106 | 58 | 58 | 14 | 47 | 51 | 2 | 0 | 0 | 1 | 9 | 5 | 3 | 5.51 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 54 | 16 | 16 | 8 | 7 | 5.37 | .338 | 1.49 | 10.1 | 3.3 | 4.0 | 105.2 | 118 | 66 | 63 | 19 | 39 | 47 | 6 | 0 | 0 | 0 | 7 | 5 | 4 | 5.71 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 47 | 0 | 2 | 2 | 4.32 | .286 | 1.16 | 7.8 | 2.7 | 7.2 | 66.2 | 57 | 33 | 32 | 6 | 20 | 53 | 0 | 5 | 2 | 0 | 0 | 3 | 1 | 3.62 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 38 | 0 | 2 | 4 | 4.56 | .292 | 1.24 | 7.6 | 3.6 | 7.3 | 53.1 | 45 | 28 | 27 | 10 | 21 | 43 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 5.02 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 35 | 0 | 0 | 2 | 4.99 | .324 | 1.43 | 7.5 | 5.7 | 8.1 | 30.2 | 25 | 17 | 17 | 6 | 19 | 27 | 0 | 4 | 1 | 0 | 0 | 0 | 5 | 5.70 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 46 | 18 | 0 | 1 | 0 | 4.45 | .377 | 1.81 | 10.8 | 5.7 | 8.1 | 30.1 | 36 | 15 | 15 | 3 | 19 | 27 | 0 | 5 | 0 | 0 | 0 | 0 | 1 | 4.40 |