| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 25 | 25 | 11 | 7 | 4.04 | .294 | 1.21 | 7.8 | 3.2 | 5.3 | 180.1 | 156 | 87 | 81 | 24 | 63 | 106 | 4 | 0 | 0 | 1 | 13 | 6 | 3 | 4.71 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 24 | 24 | 8 | 11 | 5.61 | .330 | 1.46 | 9.6 | 3.6 | 5.1 | 162.0 | 172 | 107 | 101 | 22 | 64 | 91 | 2 | 0 | 0 | 0 | 9 | 3 | 3 | 4.88 |
| SP | Pfiester, J.Pfiester, Jack # >> | 28 | 1906 | L | 73 | 24 | 24 | 6 | 11 | 4.24 | .288 | 1.19 | 7.7 | 3.1 | 4.6 | 176.0 | 150 | 88 | 83 | 18 | 60 | 90 | 7 | 0 | 0 | 3 | 11 | 4 | 2 | 4.40 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 24 | 24 | 10 | 9 | 4.85 | .323 | 1.43 | 9.1 | 3.8 | 4.4 | 174.1 | 175 | 104 | 94 | 22 | 74 | 86 | 6 | 0 | 0 | 0 | 9 | 1 | 8 | 4.95 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 23 | 23 | 7 | 10 | 5.15 | .326 | 1.43 | 9.1 | 3.8 | 5.0 | 141.2 | 142 | 88 | 81 | 15 | 60 | 78 | 4 | 0 | 0 | 1 | 10 | 4 | 5 | 4.64 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 59 | 0 | 2 | 3 | 4.15 | .322 | 1.41 | 8.0 | 4.8 | 10.8 | 73.2 | 65 | 34 | 34 | 6 | 39 | 88 | 0 | 6 | 0 | 0 | 0 | 1 | 1 | 3.30 |
| RP | Betancourt, R.Betancourt, Rafael # >> | 32 | 2007 | R | 77 | 51 | 0 | 6 | 7 | 5.22 | .353 | 1.64 | 12.4 | 2.5 | 8.4 | 58.2 | 80 | 35 | 34 | 9 | 16 | 54 | 0 | 6 | 2 | 0 | 0 | 0 | 0 | 3.98 |
| SP | McGinnity, J.McGinnity, Joe >> | 33 | 1904 | R | 50 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 3 | 1 | 0 | 1 | 4.50 | .231 | 0.90 | 5.4 | 2.7 | 6.3 | 10.0 | 6 | 5 | 5 | 2 | 3 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.10 |
| SP | Cuellar, M.Cuellar, Mike >> | 32 | 1969 | L | 43 | 20 | 0 | 4 | 4 | 9.11 | .390 | 1.88 | 12.0 | 5.3 | 4.0 | 27.2 | 36 | 32 | 28 | 7 | 16 | 12 | 0 | 0 | 3 | 0 | 0 | 1 | 1 | 7.37 |