| SP | Adams, B.Adams, Babe # >> | 27 | 1909 | R | 86 | 33 | 33 | 12 | 13 | 4.31 | .314 | 1.34 | 9.7 | 2.4 | 5.0 | 181.2 | 195 | 95 | 87 | 21 | 49 | 101 | 0 | 0 | 0 | 0 | 13 | 6 | 1 | 4.30 |
| SP | Mathewson, C.Mathewson, Christy † # >> | 28 | 1908 | R | 83 | 32 | 32 | 17 | 7 | 4.23 | .297 | 1.24 | 9.1 | 2.1 | 4.9 | 223.2 | 225 | 107 | 105 | 31 | 53 | 122 | 7 | 0 | 0 | 3 | 16 | 5 | 3 | 4.49 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 32 | 32 | 9 | 16 | 4.15 | .320 | 1.39 | 9.5 | 3.0 | 4.9 | 249.1 | 264 | 117 | 115 | 33 | 82 | 135 | 11 | 0 | 0 | 2 | 16 | 6 | 5 | 4.70 |
| RP | Feliz, N.Feliz, Neftali † >> | 21 | 2009 | R | 97 | 83 | 0 | 7 | 7 | 3.18 | .287 | 1.19 | 7.0 | 3.8 | 8.1 | 144.1 | 112 | 54 | 51 | 15 | 60 | 129 | 0 | 6 | 5 | 0 | 0 | 2 | 0 | 3.85 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 79 | 0 | 6 | 3 | 2.93 | .277 | 1.13 | 7.3 | 2.9 | 8.3 | 98.1 | 79 | 33 | 32 | 8 | 32 | 90 | 0 | 9 | 3 | 0 | 0 | 2 | 3 | 3.27 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 46 | 0 | 4 | 5 | 4.74 | .336 | 1.51 | 8.3 | 5.3 | 5.9 | 81.2 | 75 | 50 | 43 | 11 | 48 | 53 | 0 | 5 | 3 | 0 | 0 | 1 | 1 | 5.27 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 2 | 0 | 0 | 0 | 0.00 | .167 | 0.60 | 0.0 | 6.0 | 6.0 | 3.1 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.67 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 20 | 0 | 3 | 3 | 5.32 | .360 | 1.61 | 9.8 | 5.1 | 8.2 | 23.2 | 25 | 15 | 14 | 5 | 13 | 21 | 0 | 6 | 0 | 0 | 0 | 2 | 1 | 5.96 |