| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 34 | 34 | 12 | 17 | 4.64 | .306 | 1.32 | 9.0 | 2.8 | 8.3 | 256.0 | 257 | 133 | 132 | 31 | 80 | 237 | 12 | 0 | 0 | 4 | 16 | 1 | 4 | 3.67 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 33 | 33 | 10 | 15 | 4.89 | .306 | 1.31 | 9.0 | 2.8 | 8.9 | 215.1 | 215 | 134 | 117 | 30 | 68 | 212 | 3 | 0 | 0 | 1 | 18 | 2 | 6 | 3.82 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 71 | 32 | 32 | 8 | 14 | 4.80 | .311 | 1.33 | 9.1 | 2.9 | 5.6 | 200.2 | 203 | 114 | 107 | 24 | 64 | 124 | 2 | 0 | 0 | 1 | 17 | 5 | 4 | 4.36 |
| SP | Coveleski, S.Coveleski, Stan # >> | 28 | 1917 | R | 62 | 31 | 31 | 11 | 13 | 5.01 | .330 | 1.45 | 9.2 | 3.8 | 4.8 | 210.0 | 215 | 126 | 117 | 25 | 89 | 111 | 2 | 0 | 0 | 0 | 12 | 7 | 1 | 4.86 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 58 | 0 | 4 | 3 | 3.00 | .324 | 1.41 | 7.6 | 5.0 | 8.9 | 66.0 | 56 | 22 | 22 | 5 | 37 | 65 | 0 | 10 | 1 | 0 | 0 | 2 | 1 | 3.79 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 57 | 11 | 0 | 0 | 2 | 8.22 | .395 | 1.96 | 14.4 | 3.6 | 5.4 | 15.1 | 24 | 14 | 14 | 4 | 6 | 9 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 6.47 |