| SP | Johnson, W.Johnson, Walter # >> | 26 | 1913 | R | 95 | 18 | 18 | 7 | 6 | 4.10 | .292 | 1.20 | 9.1 | 1.8 | 5.4 | 116.1 | 117 | 56 | 53 | 8 | 23 | 69 | 0 | 0 | 0 | 0 | 11 | 4 | 1 | 3.41 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 17 | 17 | 5 | 7 | 5.52 | .333 | 1.48 | 10.1 | 3.2 | 8.7 | 88.0 | 99 | 55 | 54 | 16 | 31 | 85 | 0 | 0 | 0 | 0 | 8 | 2 | 2 | 4.56 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 45 | 0 | 3 | 5 | 4.08 | .287 | 1.19 | 7.4 | 3.3 | 7.4 | 46.1 | 38 | 23 | 21 | 5 | 17 | 38 | 0 | 22 | 5 | 0 | 0 | 1 | 2 | 3.93 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 80 | 32 | 0 | 2 | 1 | 4.39 | .332 | 1.46 | 8.1 | 5.0 | 8.6 | 41.0 | 37 | 20 | 20 | 5 | 23 | 39 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 4.44 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 27 | 0 | 0 | 2 | 7.39 | .396 | 1.89 | 10.3 | 6.8 | 11.9 | 28.0 | 32 | 25 | 23 | 6 | 21 | 37 | 0 | 0 | 1 | 0 | 0 | 2 | 1 | 5.61 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 22 | 0 | 1 | 6 | 6.10 | .351 | 1.57 | 11.2 | 3.1 | 6.8 | 41.1 | 51 | 33 | 28 | 8 | 14 | 31 | 0 | 2 | 3 | 0 | 0 | 2 | 2 | 5.20 |