| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 32 | 32 | 12 | 11 | 4.22 | .298 | 1.26 | 8.6 | 2.7 | 8.9 | 200.2 | 191 | 96 | 94 | 22 | 61 | 198 | 5 | 0 | 0 | 2 | 16 | 4 | 3 | 3.43 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 76 | 34 | 32 | 12 | 13 | 5.36 | .332 | 1.47 | 9.6 | 3.6 | 6.0 | 198.0 | 212 | 123 | 118 | 31 | 79 | 132 | 5 | 0 | 0 | 0 | 13 | 4 | 4 | 4.96 |
| SP | Darvish, Y.Darvish, Yu >> | 26 | 2013 | R | 45 | 34 | 32 | 7 | 12 | 7.23 | .387 | 1.88 | 11.4 | 5.6 | 8.6 | 155.2 | 196 | 140 | 125 | 32 | 97 | 148 | 0 | 0 | 0 | 0 | 9 | 2 | 5 | 5.69 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 92 | 0 | 6 | 8 | 4.05 | .315 | 1.35 | 9.2 | 3.0 | 8.0 | 95.2 | 97 | 44 | 43 | 8 | 32 | 84 | 0 | 33 | 7 | 0 | 0 | 3 | 0 | 3.43 |
| SU | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 94 | 0 | 3 | 2 | 4.58 | .296 | 1.25 | 7.6 | 3.6 | 8.8 | 110.0 | 93 | 59 | 56 | 21 | 44 | 107 | 0 | 4 | 5 | 0 | 0 | 2 | 1 | 4.79 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 100 | 0 | 9 | 2 | 3.17 | .287 | 1.18 | 7.2 | 3.5 | 8.8 | 119.1 | 95 | 44 | 42 | 13 | 46 | 117 | 0 | 7 | 1 | 0 | 0 | 3 | 3 | 3.69 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 76 | 0 | 5 | 3 | 3.82 | .310 | 1.32 | 7.6 | 4.4 | 7.6 | 103.2 | 87 | 48 | 44 | 16 | 50 | 87 | 0 | 2 | 1 | 0 | 0 | 3 | 2 | 4.87 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 73 | 0 | 5 | 2 | 3.61 | .317 | 1.37 | 6.9 | 5.6 | 10.7 | 94.2 | 72 | 44 | 38 | 14 | 58 | 112 | 0 | 1 | 3 | 0 | 0 | 2 | 6 | 4.47 |